NCT04207268

Brief Summary

The purpose of this study is to test the effect of group-based nutrition advice plus gardening (intervention) versus group-based nutrition advice alone on dietary intake of fruits and vegetables, physical activity, and lifetime risk for cardiovascular disease (CVD).

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Dec 2019

Typical duration for not_applicable cardiovascular-diseases

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 18, 2019

Completed
1 day until next milestone

Study Start

First participant enrolled

December 19, 2019

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 20, 2019

Completed
3.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2023

Completed
Last Updated

June 22, 2022

Status Verified

June 1, 2022

Enrollment Period

3.9 years

First QC Date

December 18, 2019

Last Update Submit

June 21, 2022

Conditions

Keywords

Cardiovascular disease

Outcome Measures

Primary Outcomes (2)

  • Plasma Carotenoids

    The primary outcome is between group differences in total plasma carotenoids from baseline to 16 weeks. Plasma carotenoids are a reliable bio-marker of dietary intake of F\&V.

    4 months

  • Self-reported dietary intake

    Investigators will also test the between group differences in self-reported servings of fruits and vegetables as assessed by 24-hour recalls.

    4 months

Secondary Outcomes (2)

  • Cardiovascular disease risk score

    4 months

  • Physical activity

    4 months

Study Arms (2)

Gardening and Nutrition Advice

EXPERIMENTAL

Participate in gardening activities, food demonstrations and nutrition advice

Behavioral: Gardening and Nutrition Advice

Nutrition Advice alone

PLACEBO COMPARATOR

Participate in only nutrition advice

Behavioral: Nutrition Advice

Interventions

Participate in gardening activities, gardening instructions and nutrition advice

Gardening and Nutrition Advice

Participate in only nutrition advice

Nutrition Advice alone

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Are at least 20 years old
  • Have transportation and are willing to travel to the Hershey Community Garden
  • Have any two health conditions or risk factors for CVD. These include, but are not limited to:
  • Any history of cardiovascular disease
  • Any family history of premature cardiovascular disease
  • Any history of stroke
  • High cholesterol
  • High blood pressure
  • Overweight/obesity (BMI \>=25)
  • Diabetes
  • Current or past Tobacco use

You may not qualify if:

  • Currently tends a vegetable garden
  • Moving out of the area in the next 4 months
  • Non-English speaking
  • Pregnant women
  • Participation in a past gardening study
  • Medical conditions or medications that limit ability to freely increase dietary intake of fruits and vegetables (e.g., kidney failure, dialysis)
  • A medical condition that precludes safe pursuit of gardening, i.e., recent heart conditions (e.g., heart failure, stroke, heart attack), recent or pending surgery, severe orthopedic conditions, pending hip/knee replacement, paralysis, dementia, blindness, unstable angina or uncontrolled arrhythmias, or uncontrolled asthma or allergies.
  • History of difficulty obtaining blood samples or fear of needles

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Penn State College of Medicine

Hershey, Pennsylvania, 17033, United States

Location

MeSH Terms

Conditions

Cardiovascular Diseases

Interventions

Gardening

Intervention Hierarchy (Ancestors)

HorticultureAgricultureTechnology, Industry, and Agriculture

Study Officials

  • Susan Veldheer, DEd, RD

    Penn State College of Medicine

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor, Department of Family and Community Medicine

Study Record Dates

First Submitted

December 18, 2019

First Posted

December 20, 2019

Study Start

December 19, 2019

Primary Completion

October 31, 2023

Study Completion

October 31, 2023

Last Updated

June 22, 2022

Record last verified: 2022-06

Data Sharing

IPD Sharing
Will not share

Locations