NCT03643146

Brief Summary

The objective of the proposed project is to evaluate the usability, acceptability, and adherence of a lifestyle and behavioral self-tracking and ePersuasive tool aimed at improving: 1) adherence to diet/nutrition (\<1500 mg of sodium/day and less than 10% daily free sugar intake), physical activity (PA) (150 minutes of moderate PA/week), and sleep guidelines (7-8 hours of sleep/day)-- and 2) control 3% reduction in systolic BP and glucose from baseline to end of study follow-up after 2 months (exploratory objective) in a sample of 20 patients with Hypertension or Diabetes. The study will utilize a Step-Wedge Design where the 20 patients will be divided into 4 wedges (5 patients in each wedge).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
23

participants targeted

Target at below P25 for not_applicable cardiovascular-diseases

Timeline
Completed

Started Oct 2020

Shorter than P25 for not_applicable cardiovascular-diseases

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 21, 2018

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 22, 2018

Completed
2.2 years until next milestone

Study Start

First participant enrolled

October 20, 2020

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2021

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2021

Completed
Last Updated

December 10, 2021

Status Verified

December 1, 2021

Enrollment Period

5 months

First QC Date

August 21, 2018

Last Update Submit

December 7, 2021

Conditions

Outcome Measures

Primary Outcomes (2)

  • User Acceptance measured by adherence to diet and nutrition using the Healthy Eating Survey

    12 Months

  • Measure of physical activity by the International Physical Activity Questionnaire (IPAQ)

    Used to assess physical activity and calculate metabolic equivalent

    12 Months

Study Arms (20)

Wedge 1- Step 1

EXPERIMENTAL
Behavioral: Control Group

Wedge 1-Step 2

EXPERIMENTAL
Behavioral: Lifestyle Management

Wedge 1-Step 3

EXPERIMENTAL
Behavioral: Lifestyle Management

Wedge 1-Step 4

EXPERIMENTAL
Behavioral: Lifestyle Management

Wedge 1-Step 5

EXPERIMENTAL
Behavioral: Lifestyle Management

Wedge 2- Step 1

EXPERIMENTAL
Behavioral: Control Group

Wedge 2-Step 2

EXPERIMENTAL
Behavioral: Control Group

Wedge 2-Step 3

EXPERIMENTAL
Behavioral: Lifestyle Management

Wedge 2-Step 4

EXPERIMENTAL
Behavioral: Lifestyle Management

Wedge 2-Step 5

EXPERIMENTAL
Behavioral: Lifestyle Management

Wedge 3-Step 1

EXPERIMENTAL
Behavioral: Control Group

Wedge 3- Step 2

EXPERIMENTAL
Behavioral: Control Group

Wedge 3- Step 3

EXPERIMENTAL
Behavioral: Control Group

Wedge 3- Step 4

EXPERIMENTAL
Behavioral: Lifestyle Management

Wedge 3- Step 5

EXPERIMENTAL
Behavioral: Lifestyle Management

Wedge 4-Step 1

EXPERIMENTAL
Behavioral: Control Group

Wedge 4- Step 2

EXPERIMENTAL
Behavioral: Control Group

Wedge 4-Step 3

EXPERIMENTAL
Behavioral: Control Group

Wedge 4-Step 4

EXPERIMENTAL
Behavioral: Lifestyle Management

Wedge 4-Step 5

EXPERIMENTAL
Behavioral: Lifestyle Management

Interventions

Will use passive ubiquitous sensing through FitBit to 1)learn behavioral profiles of subjects who have pre-HTN/HTN and/or pre-diabetes /Diabetes 2) provide personalized recommendations through mobile based messaging app that will increase the likelihood of engaging in health diet/nutrition, physical activity and sleep practices

Wedge 1-Step 2Wedge 1-Step 3Wedge 1-Step 4Wedge 1-Step 5Wedge 2-Step 3Wedge 2-Step 4Wedge 2-Step 5Wedge 3- Step 4Wedge 3- Step 5Wedge 4-Step 4Wedge 4-Step 5
Control GroupBEHAVIORAL

will receive standard medical care where research assistant will give pamphlets, with one size fits all recommendations for diet/nutrition, physical activity and sleep, to 10 subjects with comorbid HTN and T2D.

Wedge 1- Step 1Wedge 2- Step 1Wedge 2-Step 2Wedge 3- Step 2Wedge 3- Step 3Wedge 3-Step 1Wedge 4- Step 2Wedge 4-Step 1Wedge 4-Step 3

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • NYU and/or Bellevue patient
  • Diagnosed with HTN and pre-diabetes/diabetes
  • Must be English speakers
  • Ownership of a smart phone and are willing to use it to download app built in TrialX which will be free for participants
  • Must be ambulatory

You may not qualify if:

  • are unable or unwilling to provide informed consent;
  • are unable to participate meaningfully in an intervention that involves self-monitoring using software available in English (e.g., due to uncorrected sight impairment, illiterate, non-English-speaking, dementia);
  • are pregnant, are currently trying to become pregnant, or who become pregnant during the study
  • are institutionalized (e.g., in a nursing home or personal care facility, or those who are incarcerated and have limited control over self-management)
  • have had or are planning to have bariatric surgery during the study
  • have a history of heart disease, kidney disease, or retinopathy (to rule-out those with long-standing, undiagnosed T2D)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

New York University School of Medicine

New York, New York, 10016, United States

Location

MeSH Terms

Conditions

Cardiovascular Diseases

Interventions

Control Groups

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesResearch DesignMethods

Study Officials

  • Azizi Seixas, MD

    NYU Langone Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 21, 2018

First Posted

August 22, 2018

Study Start

October 20, 2020

Primary Completion

March 31, 2021

Study Completion

October 1, 2021

Last Updated

December 10, 2021

Record last verified: 2021-12

Data Sharing

IPD Sharing
Will share

Individual participant data that underlie the results reported in this article, after deidentification (text, tables, figures, and appendices).

Shared Documents
ICF
Time Frame
Proposals may be submitted up to 36 months following article publication. After 36 months the data will be available in our University's data warehouse but without investigator support other than deposited metadata. Information regarding submitting requests and accessing data may be found at (Link to be provided).
Access Criteria
Investigators whose proposed use of the data has been approved by an independent review committee ("learned intermediary") identified for this purpose.

Locations