NCT04206748

Brief Summary

The purpose of this study is to investigate whether automation of glucose monitoring data to facilitate the total number of recommended and completed SMBG checks improve clinical outcomes for women living with gestational and type 2 diabetes during pregnancy? This is a RCT

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2019

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 12, 2019

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

November 15, 2019

Completed
1 month until next milestone

First Posted

Study publicly available on registry

December 20, 2019

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 12, 2021

Completed
12 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2022

Completed
Last Updated

September 2, 2021

Status Verified

September 1, 2021

Enrollment Period

2 years

First QC Date

November 15, 2019

Last Update Submit

September 1, 2021

Conditions

Outcome Measures

Primary Outcomes (5)

  • Neonatal morbidity

    at the time of discharge (about 2-7 days after birth)

  • Neonatal gestational age at delivery

    at delivery

  • # of neonates who where Small for gestational age (SGA)

    at delivery

  • Neonatal intensive care unit (NICU) length of stay

    delivery to discharge (2-7 days)

  • # of Neonates with hyperbilirubinemia-requiring therapy.

    delivery to discharge (2-7 days)

Secondary Outcomes (10)

  • Average Neonatal Weight

    at the time of discharge (about 2-7 days after birth)

  • Maternal Mean fasting glucose

    perinatal to postpartum (32 weeks)

  • Maternal Mean post prandial glucose

    perinatal to postpartum (32 weeks)

  • Maternal # of Hypoglycemia events (<60 mg/dl)

    perinatal to postpartum (32 weeks)

  • Maternal weight gain during pregnancy

    perinatal to postpartum (32 weeks)

  • +5 more secondary outcomes

Study Arms (2)

iGlucose Smart Meter

EXPERIMENTAL
Device: iGlucose Smart Meter System

Rx glucose meter

PLACEBO COMPARATOR
Device: Routine Care-RX meter

Interventions

Subjects will have routine care enhanced by use of theThe iGlucose Smart meter system. This is an example of integration of a SMBG system with internet-based technology; including cell phone notifications for reminders, feedback, and communication with clinicians

iGlucose Smart Meter

Subjects will receive routine care with the insurance prescribed glucose meter. They will self manage with traditional diabetes diary.

Rx glucose meter

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • All patients \>/= women 18 years of age with gestational diabetes or type 2 diabetes during pregnancy and identified by the research team and consented before 30.6 weeks.
  • Non-anomalous singletons
  • Ability to provide informed consent

You may not qualify if:

  • Patients with Type 1 diabetes
  • Patients with fetal major congenital abnormalities
  • Patients identified/referred after 30.6 weeks

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The University of Texas Health Science Center at Houston

Houston, Texas, 77030, United States

RECRUITING

MeSH Terms

Conditions

Diabetes, GestationalPregnancy in Diabetics

Condition Hierarchy (Ancestors)

Pregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesDiabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

November 15, 2019

First Posted

December 20, 2019

Study Start

November 12, 2019

Primary Completion

November 12, 2021

Study Completion

November 1, 2022

Last Updated

September 2, 2021

Record last verified: 2021-09

Data Sharing

IPD Sharing
Will not share

Locations