NCT04195178

Brief Summary

The investigators are interested in studying why experienced clinicians make specific decisions regarding the monitoring of patients' physiological states and why clinicians might make decisions that are contrary to current best practices or known evidence. More generally, the program objective is to refine and validate a novel methodology to delineate clinicians' decision-making strategies. More specifically, the investigators will study the decision to reverse neuromuscular blockade at the end of an anesthetic. This clinical decision will be studied in this project because: 1) it has been well documented that a substantial percentage of practitioners do not follow best practices; 2) the variables are relatively circumscribed and well described; and 3) it can be framed as a binary decision. The investigators propose to conduct an observational mixed-methods study developing and using clinical vignettes and cognitive interviews to better understand the decision-making approaches and preferences of clinically active anesthesia providers with regard to their decision-making during clinical anesthesia cases. After developing clinical vignettes and related questions, the investigators will first obtain detailed demographic and clinical practice variables from the participants via a survey. Participants will then review multiple vignettes that present different clinical situations that focus on decisions to reverse neuromuscular blockade and/or extubate the patient. Each participant will provide their decisions for each vignette. The investigators will then conduct an audiotaped interview, using cognitive task analysis methods, to ascertain the factors that played a role in these decisions.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
154

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Aug 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 30, 2019

Completed
11 days until next milestone

First Posted

Study publicly available on registry

December 11, 2019

Completed
3.6 years until next milestone

Study Start

First participant enrolled

August 3, 2023

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2024

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

February 13, 2026

Completed
Last Updated

February 13, 2026

Status Verified

February 1, 2026

Enrollment Period

1.4 years

First QC Date

November 30, 2019

Results QC Date

September 16, 2025

Last Update Submit

February 11, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Accuracy on 9-item NMMR Knowledge Test

    Percent correct on 9-item test of evidence-based knowledge about neuromuscular monitoring and reversal

    Day of enrollment only

  • Confidence in NMMR Knowledge

    % confidence (0-100) in the correctness of participant's response on the knowledge test

    Day of enrollment

Study Arms (1)

Anesthesia Providers

Clinically active anesthesia providers

Eligibility Criteria

Age21 Years - 80 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Clinically active anesthesia providers

You may qualify if:

  • Clinically active experienced anesthesia providers

You may not qualify if:

  • Anesthesia providers who are no longer practicing or clinically active

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Vanderbilt University Medical Center

Nashville, Tennessee, 37203, United States

Location

Results Point of Contact

Title
Matthew B Weinger, MD
Organization
Vanderbilt University Medical Center

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

November 30, 2019

First Posted

December 11, 2019

Study Start

August 3, 2023

Primary Completion

December 31, 2024

Study Completion

December 31, 2024

Last Updated

February 13, 2026

Results First Posted

February 13, 2026

Record last verified: 2026-02

Locations