NCT04178499

Completed

Smoking: Cytokines in Vitreous and Aqueous Humor

Medical University of Graz Source

Other study identifiers

Sponsor study identifier

30-107 ex 17/18

Study Type

observational

Actual enrollment (reported)

50

Locations

0 countries

Sites

N/A

Timeline

Study Start

January 1, 2012

Actual (reported)

Primary Completion

January 1, 2015

Actual (reported)

Study Completion

June 1, 2019

Actual (reported)

Brief Summary

Smoking is a risk factor for ophthalmologic diseases. Inflammation might play a role in their pathogenesis. This study elucidates intraocular cytokine profiles in smokers and non smokers.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Actual enrollment (reported): 50 participants
Study completion date: June 1, 2019
Actual (reported)
Listed locations: 0 countries · 0 sites

Trial Relationships

Click on a node to explore related trials.

Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
January 1, 2012
Actual (reported)
Primary Completion
January 1, 2015
Actual (reported)
Study Completion
June 1, 2019
Actual (reported)
First Submitted
November 18, 2019
Actual (reported)
First Posted
November 26, 2019
Actual (reported)

Last Updated: November 26, 2019
Status Verified: November 2019
Last Update Submitted: November 25, 2019

Conditions

Smoking

Outcome Measures

Primary Outcomes (1)

cotinine
Concentration of intraocular cotinine
At the time of vitrectomy procedure

Study Arms (2)

smokers

active smokers

Diagnostic Test: cytokine analysis

non-smokers

never smokers

Diagnostic Test: cytokine analysis

Interventions

cytokine analysisDiagnostic test

analysis of intraocular cytokines

non-smokerssmokers

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodProbability Sample

Study Population

patients scheduled for vitrectomy at the Medical University of Graz/Austria

You may qualify if:

scheduled vitrectomy and/or cataract surgery

Sponsors & Collaborators

Medical University of Graz
Otherlead

Biospecimen

Retention: SAMPLES WITHOUT DNA

Vitreous humor Aqueous humor Serum

MeSH Terms

Conditions

Smoking

Condition Hierarchy (Ancestors)

Behavior

Enrollment

50 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: ECOLOGIC OR COMMUNITY
Time Perspective: CROSS SECTIONAL
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

November 18, 2019

First Posted

November 26, 2019

Study Start

January 1, 2012

Actual (reported)

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The Compliance of Varenicline With Short-massage

Unknown

NCT01429129

Randomized Controlled Trial of Mailed Nicotine Replacement Therapy to Canadian Smokers

Phase 4Completed

NCT02179424

Promoting Tobacco Control and Smoking Cessation in Workplaces [Phase I]

Not ApplicableCompleted

NCT01689168

Chiropractic Treatment With Counseling Versus Counseling Alone for Promoting Smoking Cessation

Phase 1Terminated

NCT01585610

Motivating Smokers With Mobility Impairments to Quit Smoking

Phase 3Unknown

signed informed consent

You may not qualify if:

diabetes
uveitis
rheumatologic disease
anti-inflammatory/immunomodulatory medications
st.p. intravitreal injections
st.p. glaucoma surgery
cataract surgery on the eye to be examined within the past 6 months

Contact the study team to confirm eligibility.

Primary Completion

January 1, 2015

Actual (reported)

Study Completion

June 1, 2019

Actual (reported)

Last Updated

November 26, 2019

Record last verified: 2019-11

Data Sharing

IPD Sharing: Will not share

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT04178499
Data provider: ClinicalTrials.gov
Source updated: 2019-11-26
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:28:42 UTC

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Outcome Measures

Primary Outcomes (1)

Study Arms (2)

smokers

non-smokers

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record