NCT04161326

Brief Summary

Myopia is one of the major causes of low visual acuity during childhood. It is generally more prevalent in urban areas than in rural areas. Current evidence does not address our understanding of the myopia incidence and development and associated risk geographic factors, such as green spaces. Therefore, our study aimed to evaluate the association between geographic factors and myopia base on a population-based large-scaled cohort design.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2016

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2016

Completed
3.9 years until next milestone

First Submitted

Initial submission to the registry

November 11, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 13, 2019

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2019

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2021

Completed
Last Updated

February 25, 2020

Status Verified

February 1, 2020

Enrollment Period

4 years

First QC Date

November 11, 2019

Last Update Submit

February 22, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • the changes of spherical equivalent refractive (RSE)

    A multi-linear regression was used.

    up to 3 years

Eligibility Criteria

Age6 Years - 9 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

A prospective longitudinal cohort study of schoolchildren who studied in the 1st to 4th grades was performed.

You may qualify if:

  • schoolchildren in the 1st to 4th grades

You may not qualify if:

  • schoolchildren unwilling to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Zhongshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, Guangdong, 510000, China

RECRUITING

MeSH Terms

Conditions

Refractive ErrorsMyopia

Condition Hierarchy (Ancestors)

Eye Diseases

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

November 11, 2019

First Posted

November 13, 2019

Study Start

January 1, 2016

Primary Completion

December 30, 2019

Study Completion

December 30, 2021

Last Updated

February 25, 2020

Record last verified: 2020-02

Locations