Burden of Influenza at Emergency Department Level : BIED

NCT04153331 | Completed

• 1 other identifier: 69HCL19_0755
• Study Type: interventional
• Target: 2,487
• Locations: 1 country
• Sites: 1

Brief Summary

Seasonal influenza surveillance in France relies on several sources to detect the onset of the epidemic early, as well as to estimate the severity of epidemics and their impact on the health system. However, the data collected do not fully measure the impact of epidemics on the hospital system. Increasing the investigator's knowledge of the impact of influenza on the hospital system, particularly on emergencies, which are the most affected service, is essential to better adapt the resources put in place to care for patients. The study will allow a better understanding of the influenza burden, by systematically documenting the severe events (i.e. requiring consultations to the Emergency Rooms) that are triggered by influenza but not necessarily reported/recorded as influenza.

Conditions

Emergencies; Flu

Outcome Measures

Primary Outcomes (1)

• Proportion of laboratory confirmed influenza among patients admitted to Emergency Room during the influenza season

  The proportion of laboratory confirmed influenza cases will be calculated by dividing the number of patients with laboratory confirmed influenza by the total number of patients included

  1 day (at admission)

Secondary Outcomes (4)

• Proportion of patients with co-morbidities

  1 day (at admission)

• Proportion of patients with laboratory confirmed influenza and related outcomes

  1 day (at admission)

• Proportion of patients who consult for other causes than influenza

  1 day (at admission)

• Proportion of asymptomatic influenza cases among patients with laboratory confirmed influenza

  1 day (at admission)

Study Arms (1)

Patients admitted to emergency department with medical cause

EXPERIMENTAL

Patient included in emergency with a nasal swab

Other: Nasal swab

Interventions

Nasal swab OTHER

Patient included in emergency with a nasal swab

Patients admitted to emergency department with medical cause

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age \> 18 years
• Consultation for a medical cause

You may not qualify if:

• Consultation for a non-medical cause (trauma...)
• Pregnant, parturient and lactating women
• Persons deprived of their liberty
• Persons of full age who are subject to a legal protection measure
• Persons not affiliated to a social security system

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Service Hygiène, Epidémiologie et Prévention

Lyon, 69003, France

Location

Related Publications (1)

• Amour S, Rubio AP, Orsi A, Oppert M, Loebermann M, Del Pozo Vegas C, Tazarourte K, Douplat M, Jacquin L, Icardi G, Walker J, Glass A, Nealon J, Chaves SS; FERS Study Group; Bricout H, Vanhems P. Influenza in Adults Seeking Care at Seven European Emergency Departments: A Prospective Active Surveillance During the 2019-2020 Influenza Season. Influenza Other Respir Viruses. 2024 Nov;18(11):e70040. doi: 10.1111/irv.70040.

  PMID: 39568106 RESULT

MeSH Terms

Conditions

Emergencies; Influenza, Human

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Respiratory Tract Infections; Infections; Orthomyxoviridae Infections; RNA Virus Infections; Virus Diseases; Respiratory Tract Diseases

Study Officials

• Philppe VANHEMS, MD

  Service Hygiène, Epidémiologie et Prévention

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 4, 2019
• First Posted: November 6, 2019
• Study Start: January 13, 2020
• Primary Completion: March 9, 2020
• Study Completion: March 9, 2020
• Last Updated: September 4, 2025

Record last verified: 2020-01

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)