Muscle Viscoelastic Properties In Birth Palsy

NCT04148131 | Completed DMC

• 1 other identifier: kıvançOBPP
• Study Type: observational
• Target: 74
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of study was to observe changes in denervated muscles viscoelastic properties and motor performance of OBPP children. Viscoelastic properties have a significant effect on muscle performance; however have not investigated yet in denervated muscle. Hypothesized that the viscoelastic properties of denervated muscles are different than healthy side muscles and can vary depending on the age groups. 74 patients who have C5-C6 root lesion were enrolled to the study. The patients were grouped according to their age groups: 1-5 months, 6-24 months and 25-36 months. Myoton-3 myotonometric measuring device was used to measure the viscoelastic properties (tone, elasticity and stiffness) of deltoid, biceps brachii. Active Movement Scale were used to evaluate the motor function of the muscles. There were difference in muscle viscoelastic properties depending on age group. Children aged 0-5 months showed significant difference in deltoid muscle tone (p=0.0001), stiffness (p=0.0001), biceps brachii muscle tone (p=0.0001) and stiffness (p=0.0001), when compared with other groups (denervated side was lower in values). Therefore, it is in our opinion that in follow-up, clinical assessment of viscoelastic properties will be useful for monitoring denervated muscle; also treatment programs and purposes for OBPP should be varying according to the muscle properties.

Conditions

Birth Injuries; Obstetric; Injury

Keywords

Brachial Plexus; birth injury

Outcome Measures

Primary Outcomes (1)

• Myotone-3, Viscoelastic Properties Measurement

  Viscoelastic properties of deltoid and biceps brachii muscles in both denervated and healthy sides were analyzed with using Myoton-3 device, which is a reliable handhold device for measuring viscoelastic properties of muscles by recording the damped mechanical oscillations; and provides objective, painless and noninvasive way to measure quantitative value of the muscle tone, stiffness and elasticity, invented at the University of Tartu in Estonia (Müomeetria AS, Estonia, EU) (ICC: 0,80-0,93).

  a day (single measurement)

Secondary Outcomes (1)

• Active Movement Scale

  a day (single measurement)

Study Arms (3)

Group 1, 0-5 months old

Children which is Obstetric brachial plexus palsy and 0-5 months old age have Naracas type 2 lesion.

Group 2, 6-24 months old

Children which is Obstetric brachial plexus palsy and 6-24 months old age have Naracas type 2 lesion.

Group 3, 25-36 months old

Children which is Obstetric brachial plexus palsy and 25-36 months old age have Naracas type 2 lesion.

Eligibility Criteria

• Age: Up to 36 Months
• Sex: all
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

* The Population have Obstetric Brachial Plexus Palsy * Seventy-four (25 boys, 49 girls) children aged between 1-36 months (15.12±10.58) with Narakas type 2 injury (C5-C6 upper trunk involvement) were enrolled to the study

You may qualify if:

• being treated with conventional physiotherapy and routinely followed up by our clinic since birth.

You may not qualify if:

• having a history of orthopaedic or neurologic surgery,
• having low birth weight or premature birth history,
• having a systemic, genetic or neuromuscular disease.

Sponsors & Collaborators

• Hacettepe University: lead

MeSH Terms

Conditions

Birth Injuries; Wounds and Injuries

Condition Hierarchy (Ancestors)

Infant, Newborn, Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, MSc

Study Record Dates

• First Submitted: October 25, 2019
• First Posted: November 1, 2019
• Study Start: May 28, 2015
• Primary Completion: June 30, 2016
• Study Completion: December 20, 2016
• Last Updated: November 1, 2019

Record last verified: 2019-10

Data Sharing

• IPD Sharing: Will not share