Nonverbal Communication in Aged People
MAMUS
2 other identifiers
interventional
240
1 country
1
Brief Summary
Musical interventions improve the emotional state of patients with Alzheimer's disease (AD) while having a positive impact on the caregiver's well-being. However, the factors that could be responsible for this positive effect remain unknown. Among these, the sensory-motor synchronization (SMS) of movements to the musical rhythm, frequently observed during musical activities and possible up to the advanced stages of AD, could modulate the emotional state. Several recent studies have shown that rhythmic training (or SMS) influences the organism at the motor, cognitive and social levels while activating the cerebral reward circuit. This action that generates pleasure also facilitates non-verbal emotional expression. However, the conditions that modulate SMS and their relationship to nonverbal communication, emotional, behavioral and cognitive state have not yet been studied in healthy or pathological elderly.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable alzheimer-disease
Started May 2018
Typical duration for not_applicable alzheimer-disease
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 17, 2018
CompletedFirst Submitted
Initial submission to the registry
January 9, 2019
CompletedFirst Posted
Study publicly available on registry
October 31, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2021
CompletedNovember 20, 2020
November 1, 2020
3 years
January 9, 2019
November 19, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
measure of consistency (oppositive of variability)
measure of consistency (oppositive of variability) of the response corresponding to the length of a vector going from 0 (bad) to 1(very good response). This measure is completed by another measure of asynchrony.
Baseline, before SMS task
measure of asynchrony.
The asynchrony assess the accuracy of the movements in ms. If the participant anticipated the tap relative to the musical beat, the value is negative, if the participant delayed the tap, the value is positive. A perfect tap is 0 in this case
Baseline, before SMS task
Secondary Outcomes (13)
Measurement of the Music Balance Board (cf. primary outcome) during music in the presence of a real experimenter
Baseline, before SMS task
Measurement of the Music Balance Board (cf. primary outcome) during music in the presence of a virtual experimenter;
after SMS task, an average after 45 min
Measurement of the Music Balance Board (cf. primary outcome) during metronome in the presence of a real experimenter
after SMS task, an average after 45 min
Measurement of the Music Balance Board (cf. primary outcome) during metronome in the presence of a virtual experimenter.
after SMS task, an average after 45 min
Decoding of non-verbal behaviors during the synchronization task
after SMS task, an average after 45 min
- +8 more secondary outcomes
Study Arms (2)
Patients with neurodegenerative disease
ACTIVE COMPARATORPatients with neurodegenerative disease (AD or related disease)
People with no neuropathological disease
ACTIVE COMPARATORInterventions
The SSM is measured with an innovative tool (Music Balance Board) developed at the University of Ghent (Belgium) and specially designed to record the movements of the elderly in a natural and comfortable position This chair is equipped with a tablet and sensors that record the movements of the hand and body during the SSM to a musical sequence. The analysis will focus on the difference between the participant's striking and the beat of the music measured using this chair.
Eligibility Criteria
You may qualify if:
- Cases : Patients with neurodegenerative disease (AD or related disease)
- Native French Language
- Corrected auditory and/or visual deficiency
- Right-handed
- Image rights consent signed by the patient Controls: People with no neuropathological disease
- Native French Language
- Corrected auditory and/or visual deficiency
- Right-handed
- Image rights consent signed by the control
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University Hospital, Lillelead
- France Alzheimercollaborator
Study Sites (1)
Hôpital les Bateliers, CHU
Lille, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
François Puissieux, MD,PhD
University Hospital, Lille
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 9, 2019
First Posted
October 31, 2019
Study Start
May 17, 2018
Primary Completion
May 1, 2021
Study Completion
May 1, 2021
Last Updated
November 20, 2020
Record last verified: 2020-11
Data Sharing
- IPD Sharing
- Will not share