NCT04145063

Brief Summary

This study aims to compare three groups of patients who underwent uncomplicated ureteroscopic lithotripsy (URSL) to evaluate whether stents could be eliminated after the procedure

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2016

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 2, 2016

Completed
3.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2019

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

October 28, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 30, 2019

Completed
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2020

Completed
Last Updated

August 18, 2021

Status Verified

August 1, 2021

Enrollment Period

3.3 years

First QC Date

October 28, 2019

Last Update Submit

August 17, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Visual Analog Score (VAS)

    Visual Analog Score (VAS) for flank pain and dysuria score, urgency, frequency, suprapubic pain, hematuria, analgesia requirement, operative time, re-hospitalization, and return to normal physical activity. This is a widely-used scale. It a unidimensional measure of pain intensity. It is administered as a straight horizontal line orientated from the left (worst) to the right (best) , where the patient indicates their situation.

    1 week

Study Arms (3)

uncomplicated ureteroscopic lithotripsy with DJ-US

NO INTERVENTION

Following uncomplicated uretroscopic lithotripsy, a double J uretric stent will be placed (usually the standard of care)

uncomplicated ureteroscopic lithotripsy without US

ACTIVE COMPARATOR

Following uncomplicated uretroscopic lithotripsy no uretric stent will be placed

Other: no stent

uncomplicated ureteroscopic lithotripsy with DJ-US-string

NO INTERVENTION

Following uncomplicated uretroscopic lithotripsy, a double J uretric stent with an extraxtion string will be placed

Interventions

following uretroscopy, no stent will be placed

uncomplicated ureteroscopic lithotripsy without US

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18 years or older
  • unilateral ureteric stones managed by ureteroscopy

You may not qualify if:

  • Stone size \< 2 cm
  • bilateral ureteral stones
  • incomplete stone removal due to impacted stones
  • failed ureteroscopic access to the stone
  • stone migration to the kidney
  • pregnancy
  • active urinary tract infection
  • solitary kidney
  • ureteral stent placed preoperatively
  • severe mucosal injury or perforation
  • suspected additional ureteral pathology such as ureteral stricture
  • urothelial carcinoma or polyp.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Jordan University Hospital

Amman, 11942, Jordan

Location

MeSH Terms

Conditions

Ureterolithiasis

Condition Hierarchy (Ancestors)

Ureteral DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesUrolithiasisMale Urogenital Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

October 28, 2019

First Posted

October 30, 2019

Study Start

February 2, 2016

Primary Completion

June 1, 2019

Study Completion

December 1, 2020

Last Updated

August 18, 2021

Record last verified: 2021-08

Locations