Diastolic Dysfunction PPCM in Patients With Documented Left Ventricular Systolic Function Recovery

NCT04143997 | Withdrawn

• 1 other identifier: PRO00036227
• Study Type: observational
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this project is to evaluate parameters of diastolic dysfunction assessed by clinical echocardiogram in patients who have had recovery of systolic function.

Conditions

Peripartum Cardiomyopathy; Diastolic Dysfunction

Outcome Measures

Primary Outcomes (1)

• Report the incidence of diastolic dysfunction in peripartum cardiomyopathy patients with full systolic function recovery

  Investigators will review and report incidence of remaining diastolic dysfunction for local patient population which have recovered systolic function.

  January 1, 2014 through September 1, 2019

Study Arms (1)

PPCM with Diastolic Dysfunction & Normal Systolic Function

The patient population examined will include patients diagnosed with peripartum cardiomyopathy who have diastolic dysfunction and normal systolic function.

Diagnostic Test: A clinical Transthoracic echocardiogram

Interventions

A clinical Transthoracic echocardiogram DIAGNOSTIC_TEST

A previously clinically completed transthoracic echocardiogram will be utilized to assess for diastolic dysfunction in the presence of normal systolic function for patients with previously diagnosed peripartum cardiomyopathy.

PPCM with Diastolic Dysfunction & Normal Systolic Function

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adults with a current or prior diagnosis of peripartum cardiomyopathy and documented recovered of left ventricular systolic function.

You may qualify if:

• Female.
• Greater than age 18 years at the time of peripartum cardiomyopathy diagnosis.
• Adults with a current or prior diagnosis of peripartum cardiomyopathy and documented recovered of left ventricular systolic function.
• Documented recovered of LV systolic performance defined as LVEF \> 50%.

You may not qualify if:

• No pregnancy history.
• No diagnosis of peripartum cardiomyopathy.
• Non-recovery of LV systolic function.

Sponsors & Collaborators

• Medical College of Wisconsin: lead

Study Sites (1)

Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States

Location

MeSH Terms

Conditions

Peripartum Cardiomyopathy

Condition Hierarchy (Ancestors)

Pregnancy Complications, Cardiovascular; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Cardiomyopathies; Heart Diseases; Cardiovascular Diseases

Study Officials

• Sarah Thordsen, MD

  Medical College of Wisconsin

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 28, 2019
• First Posted: October 30, 2019
• Study Start: November 1, 2019
• Primary Completion: January 29, 2021
• Study Completion: January 29, 2021
• Last Updated: August 23, 2024

Record last verified: 2024-08

Locations

US (1)