Detection of Sinusoidal Obstruction Syndrome With Ultrasound After Allogeneic HSCT
A Real-life Study About Prediction of Sinusoidal Obstruction Syndrome With Ultrasound and Elastography Before Allogeneic Hematopoietic Stem Cell Transplantation
1 other identifier
observational
114
0 countries
N/A
Brief Summary
We would like conduct a real-life study in our center to evaluate the early detection of sinusoidal obstruction syndrome with hepatic ultrasound or elastography before allogeneic hematopoietic stem cell transplantation.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Sep 2016
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2018
CompletedFirst Submitted
Initial submission to the registry
October 25, 2019
CompletedFirst Posted
Study publicly available on registry
October 28, 2019
CompletedSeptember 26, 2025
September 1, 2025
2 years
October 25, 2019
September 23, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
incidence in the cohort of sinusoidal obstruction syndrome
incidence
up to 24 months
Study Arms (1)
patients from September 2016 to September 2018
all patients underwent allogeneic hematopoietic stem cell transplantation
Interventions
Eligibility Criteria
all patients transplanted for hematologic disease
You may qualify if:
- all adult patients with allogeneic hematopoietic stem cell transplantation in Nancy University Hospital between Sep 2016 and dec 2024
You may not qualify if:
- age \< 18 years old
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (2)
Mohty M, Malard F, Abecassis M, Aerts E, Alaskar AS, Aljurf M, Arat M, Bader P, Baron F, Bazarbachi A, Blaise D, Ciceri F, Corbacioglu S, Dalle JH, Dignan F, Fukuda T, Huynh A, Masszi T, Michallet M, Nagler A, NiChonghaile M, Okamoto S, Pagliuca A, Peters C, Petersen FB, Richardson PG, Ruutu T, Savani BN, Wallhult E, Yakoub-Agha I, Duarte RF, Carreras E. Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation. Bone Marrow Transplant. 2016 Jul;51(7):906-12. doi: 10.1038/bmt.2016.130. Epub 2016 May 16.
PMID: 27183098BACKGROUNDLassau N, Auperin A, Leclere J, Bennaceur A, Valteau-Couanet D, Hartmann O. Prognostic value of doppler-ultrasonography in hepatic veno-occlusive disease. Transplantation. 2002 Jul 15;74(1):60-6. doi: 10.1097/00007890-200207150-00011.
PMID: 12134100BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Maud D'Aveni, MD, PhD
Université de Lorraine - CHRU de Nancy
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 25, 2019
First Posted
October 28, 2019
Study Start
September 1, 2016
Primary Completion
September 1, 2018
Study Completion
September 1, 2018
Last Updated
September 26, 2025
Record last verified: 2025-09
Data Sharing
- IPD Sharing
- Will not share