A National Study for Blood Based Response Monitoring of B-cell Lymphoma Patients
HO902DLBCL
1 other identifier
observational
250
1 country
60
Brief Summary
Observational prospective study. Patients with DLBCL and HGBCL will be enrolled in the study to collect samples for developing a blood based assay allowing biomarker driven treatment in the future.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2020
Typical duration for all trials
60 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 23, 2019
CompletedFirst Posted
Study publicly available on registry
October 25, 2019
CompletedStudy Start
First participant enrolled
March 17, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2023
CompletedApril 26, 2023
April 1, 2023
3.2 years
October 23, 2019
April 25, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Tissue material
For genomic analysis and clinical outcome data
24 months
Interventions
No intervention
Eligibility Criteria
Patients who meet the eligibility criteria
You may qualify if:
- Patients diagnosed with newly diagnosed DLBCL (including HGBCL- NOS and HGBCL-DH) according to WHO classification 2016
- Ann Arbor stage II-IV
- Age ≥ 18 years
You may not qualify if:
- \- Patients with limited stage I, II disease planned to receive 3 cycles of R-CHOP + radiotherapy, or 4 x R-CHOP+ 2R
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (60)
NL-Den Bosch-JBZ
's-Hertogenbosch, Netherlands
NL-Alkmaar-NWZ
Alkmaar, Netherlands
NL-Almelo-ZGTALMELO
Almelo, Netherlands
NL-Almere-FLEVOZIEKENHUIS
Almere Stad, Netherlands
NL-Amersfoort-MEANDERMC
Amersfoort, Netherlands
NL-Amstelveen-AMSTELLAND
Amstelveen, Netherlands
NL-Amsterdam-AMC
Amsterdam, Netherlands
NL-Amsterdam-OLVG
Amsterdam, Netherlands
NL-Amsterdam-VUMC
Amsterdam, Netherlands
NL-Arnhem-RIJNSTATE
Arnhem, Netherlands
NL-Assen-WZA
Assen, Netherlands
NL-Beverwijk-RKZ
Beverwijk, Netherlands
NL-Breda-AMPHIA
Breda, Netherlands
NL-Capelle a/d IJssel-YSL
Capelle aan den IJssel, Netherlands
NL-Delft-RDGG
Delft, Netherlands
NL-Deventer-DZ
Deventer, Netherlands
NL-Dirksland-VANWEELBETHESDA
Dirksland, Netherlands
NL-Doetinchem-SLINGELAND
Doetinchem, Netherlands
NL-Dordrecht-ASZ
Dordrecht, Netherlands
NL-Ede-ZGV
Ede, Netherlands
NL-Eindhoven-CATHARINA
Eindhoven, Netherlands
NL-Eindhoven-MAXIMAMC
Eindhoven, Netherlands
NL-Emmen-SCHEPER
Emmen, Netherlands
NL-Enschede-MST
Enschede, Netherlands
NL-Geldrop-STANNA
Geldrop, Netherlands
NL-Goes-ADRZ
Goes, Netherlands
NL-Gorinchem-BEATRIX
Gorinchem, Netherlands
NL-Gouda-GROENEHART
Gouda, Netherlands
NL-Groningen-UMCG
Groningen, Netherlands
NL-Hardenberg-SAXENBURGH
Hardenberg, Netherlands
NL-Harderwijk-STJANSDALHARDERWIJK
Harderwijk, Netherlands
NL-Heerenveen-TJONGERSCHANS
Heerenveen, Netherlands
NL-Helmond-ELKERLIEK
Helmond, Netherlands
NL-Hoofddorp-SPAARNEGASTHUIS
Hoofddorp, Netherlands
NL-Hoorn-DIJKLANDERHOORN
Hoorn, Netherlands
NL-Leeuwarden-MCL
Leeuwarden, Netherlands
NL-Leiden-LUMC
Leiden, Netherlands
NL-Maastricht-MUMC
Maastricht, Netherlands
NL-Nieuwegein-ANTONIUS
Nieuwegein, Netherlands
NL-Nijmegen-CWZ
Nijmegen, Netherlands
NL-Roermond-LZR
Roermond, Netherlands
NL-Roosendaal-BRAVIS
Roosendaal, Netherlands
NL-Rotterdam-ERASMUSMC
Rotterdam, Netherlands
NL-Rotterdam-IKAZIA
Rotterdam, Netherlands
NL-Rotterdam-MAASSTADZIEKENHUIS
Rotterdam, Netherlands
NL-Rotterdam-SFG
Rotterdam, Netherlands
NL-Sneek-ANTONIUSSNEEK
Sneek, Netherlands
NL-Spijkenisse-SPIJKENISSEMC
Spijkenisse, Netherlands
NL-Terneuzen-ZORGSAAM
Terneuzen, Netherlands
NL-Den Haag-HAGA
The Hague, Netherlands
NL-Den Haag-HMCWESTEINDE
The Hague, Netherlands
NL-Tiel-RIVIERENLAND
Tiel, Netherlands
NL-Tilburg-ETZ
Tilburg, Netherlands
NL-Uden-BERNHOVEN
Uden, Netherlands
NL-Utrecht-DIAKONESSENUTRECHT
Utrecht, Netherlands
NL-Utrecht-UMCUTRECHT
Utrecht, Netherlands
NL-Venlo-VIECURI
Venlo, Netherlands
NL-Winterswijk-SKBWINTERSWIJK
Winterswijk, Netherlands
NL-Zutphen-GELREZUTPHEN
Zutphen, Netherlands
NL-Zwolle-ISALA
Zwolle, Netherlands
Study Officials
- PRINCIPAL INVESTIGATOR
M.E.D. Chamuleau, MD, PhD
VUmc
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 23, 2019
First Posted
October 25, 2019
Study Start
March 17, 2020
Primary Completion
June 1, 2023
Study Completion
June 1, 2023
Last Updated
April 26, 2023
Record last verified: 2023-04
Data Sharing
- IPD Sharing
- Will not share