Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 50/100

Failure Rate

13.9%

5 terminated/withdrawn out of 36 trials

Success Rate

50.0%

-36.5% vs industry average

Late-Stage Pipeline

42%

15 trials in Phase 3/4

Results Transparency

0%

0 of 5 completed trials have results

Key Signals

12 recruiting

Enrollment Performance

Analytics

Phase 2
16(45.7%)
Phase 3
15(42.9%)
Phase 1
3(8.6%)
N/A
1(2.9%)
35Total
Phase 2(16)
Phase 3(15)
Phase 1(3)
N/A(1)

Activity Timeline

Global Presence

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Clinical Trials (36)

Showing 20 of 36 trials
NCT04628026Phase 3Recruiting

Phase III Study of Induction and Consolidation Chemotherapy With Venetoclax in Patients With Newly Diagnosed AML or MDS-EB-2

Role: collaborator

NCT05502250Phase 2Active Not Recruiting

Tislelizumab, Gemcitabine and Cisplatin for R/R Hodgkin Lymphoma Followed by Tislelizumab Consolidation in Patients in Metabolic Complete Remission

Role: lead

NCT06067048Phase 2Active Not Recruiting

Zanubrutinib in Primary Cold Agglutinin Disease

Role: lead

NCT01208766Phase 3Completed

Study to Compare VMP With HDM Followed by VRD Consolidation and Lenalidomide Maintenance in Patients With Newly Diagnosed Multiple Myeloma

Role: lead

NCT04523428Phase 2Recruiting

REtreatment With VEnetoclax and Acalabrutinib After Venetoclax Limited Duration (REVEAL)

Role: lead

NCT03463057Phase 2Active Not Recruiting

The Feasibility and Clinical Efficacy of Atezolizumab Consolidation Treatment in High Risk (IPI > 2) DLBCL

Role: lead

NCT06220032Phase 3Recruiting

Prevention of Anthracycline-Induced Cardiac Dysfunction With Dexrazoxane in Patients With Diffuse Large-B Cell Lymphoma

Role: lead

NCT07223814Phase 3Not Yet Recruiting

Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)

Role: lead

NCT07075016Phase 3Recruiting

Ivosidenib and Azacitidine With or Without Venetoclax in Adult Patients With Newly Diagnosed IDH1-Mutated AML or MDS/AML Considered Ineligible for Intensive Chemotherapy

Role: lead

NCT06652438Phase 3Recruiting

Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML

Role: lead

NCT06605586Phase 1Recruiting

Tasquinimod in Patients with Myelofibrosis Refractory to or Intolerant for JAK2 Inhibition

Role: lead

NCT02950051Phase 3Completed

Standard Chemoimmunotherapy (FCR/BR) Versus Rituximab + Venetoclax (RVe) Versus Obinutuzumab (GA101) + Venetoclax (GVe) Versus Obinutuzumab + Ibrutinib + Venetoclax (GIVe) in Fit Patients with Previously Untreated Chronic Lymphocytic Leukemia (CLL) Without Del(17p) or TP53 Mutation

Role: collaborator

NCT04027309Phase 3Active Not Recruiting

A Study of Gilteritinib Versus Midostaurin in Combination With Induction and Consolidation Therapy Followed by One-year Maintenance in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndromes With Excess Blasts-2 With FLT3 Mutations Eligible for Intensive Chemotherapy

Role: lead

NCT03839771Phase 3Active Not Recruiting

A Study of Ivosidenib or Enasidenib in Combination With Induction Therapy and Consolidation Therapy, Followed by Maintenance Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myedysplastic Syndrome EB2, With an IDH1 or IDH2 Mutation, Respectively, Eligible for Intensive Chemotherapy

Role: lead

NCT05641428Phase 2Recruiting

Comparison of Point-of-care Produced CAR T-cell with Commercial CAR T-cells in Patients with R/R LBCL

Role: collaborator

NCT04097470Phase 2Active Not Recruiting

Tolerability and Efficacy of Midostaurin to 10-day Decitabine in Unfit Adult AML and High Risk MDS Patients

Role: lead

NCT03541083Phase 2Active Not Recruiting

Blinatumomab Added to Prephase and Consolidation Therapy in Precursor B-acute Lymphoblastic Leukemia in Adults.

Role: lead

NCT06187441Phase 3Recruiting

FeAsiBility of a Treatment Free Interval in Newly Diagnosed MM Patients Treated With Daratumumab-lenalidomide-dexamethasone (HOVON174MM)

Role: lead

NCT04876716Phase 3Terminated

Azole-echinocandin Combination Therapy for Invasive Aspergillosis

Role: collaborator

NCT05791409Phase 1Recruiting

Venetoclax Treatment (26 Cycles) With 6 Cycles or 12 Cycles of Epcoritamab in Patients With Relapsed or Refractory CLL or SLL

Role: lead