NCT04135105

Brief Summary

Tone language refers to a language that uses fixed pitch pattern to distinguish words (Yip, 2002). Understanding the functional anatomy of the brain during lexical tone processing will provide useful hints for an effective intervention strategy such as brain stimulation. The present study investigate the cortical organisation of the brain in lexical tone perception of Cantonese speakers by the use of functional magnetic resonance imaging (fMRI).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
29

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Feb 2017

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 12, 2017

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 25, 2018

Completed
1.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2019

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

October 19, 2019

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 22, 2019

Completed
Last Updated

January 27, 2020

Status Verified

January 1, 2020

Enrollment Period

1 year

First QC Date

October 19, 2019

Last Update Submit

January 24, 2020

Conditions

Lexical ToneNeuroimagingChineseSpeech Perception

Keywords

Speech PerceptionNeuroimagingLexical ToneChinese

Outcome Measures

Primary Outcomes (1)

  • Activation areas in the brain that are responsible for lexical tone perception

    To identify the activation area(s) in the brain that are responsible for lexical tone perception in normal hearing participants

    2015-2019

Secondary Outcomes (2)

  • Accuracy rate

    2015-2019

  • Reaction Time

    2015-2019

Study Arms (1)

Normal hearing group

Right-handed, normal hearing, no reported neurological disorders

Other: Normal hearing group

Interventions

Normal hearing groupOTHER

Observational

Normal hearing group

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Recruitment via University mass mail They were paid for their participations.

You may qualify if:

  • native Cantonese speaker
  • right-handed
  • normal hearing
  • no reported of neurological disorder

You may not qualify if:

  • neurological disorder
  • left-handed
  • hearing impairment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Prince of Wales Hospital

Hong Kong, Hong Kong, China

Location

Study Officials

  • Yuet Sheung Lee, Professor

    Chinese University of Hong Kong

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Chief of Division of Speech Therapy

Study Record Dates

First Submitted

October 19, 2019

First Posted

October 22, 2019

Study Start

February 12, 2017

Primary Completion

February 25, 2018

Study Completion

September 30, 2019

Last Updated

January 27, 2020

Record last verified: 2020-01

Locations

CN(1)