NCT04133402

Brief Summary

Today, few data are available on the patient's fertility following intrauterine tamponade balloon (BTIU) used for postpartum hemorrhage (PPH) after vaginal delivery (AVB). Several studies have concluded that there are no fertility disorders after conservative surgical treatment or embolization. BTIU is an essential treatment in the management of PPH. The aim was to evaluate post-BTIU fertility and the appearance of gynecological symptoms. This is a bicentric retrospective study (Valenciennes, Lille, France), between 2012 and 2017. The data will be collected by telephone interview on fertility and various gynecological functional symptoms.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
59

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Nov 2019

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 17, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

October 21, 2019

Completed
29 days until next milestone

Study Start

First participant enrolled

November 19, 2019

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 27, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 27, 2019

Completed
Last Updated

July 1, 2020

Status Verified

October 1, 2019

Enrollment Period

1 month

First QC Date

October 17, 2019

Last Update Submit

June 29, 2020

Conditions

Keywords

Hemorrhage Post-partumFertilityUterine balloon tamponadeVaginal Birth

Outcome Measures

Primary Outcomes (1)

  • Frequency of infertility

    defined as the absence of pregnancy after 12 months of attempted pregnancy.

    7 years

Secondary Outcomes (6)

  • Time to obtain a new pregnancy evaluating the stop of contraceptionand desire for pregnancy

    7 years

  • Frequency of gynecological complications after use of an intrauterine tamponade balloon.

    7 years

  • Type of gynecological complications after use of an intrauterine tamponade balloon.

    7 years

  • the frequency of obstetric complications for the next pregnancy

    7 years

  • type of obstetrical complications

    7 years

  • +1 more secondary outcomes

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Major patients with postpartum haemorrhage after vaginal delivery between 2012 and 2017 in Valenciennes maternity and the CHRU Lille, treated by intrauterine tamponade therapy.

You may qualify if:

  • Vaginal birth
  • Post partum haemorrhage
  • Intrauterine tamponing balloon
  • Between 2012 and 2017
  • CHRU Lille and CH Valenciennes

You may not qualify if:

  • Minor patients
  • Initial intake started in another center (postpartum transfer).
  • Refusal to participate in the study
  • Invasive treatments for postpartum haemorrhage
  • Caesarean

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hôpital Roger Salengro, CHU

Lille, France

Location

MeSH Terms

Conditions

Postpartum Hemorrhage

Condition Hierarchy (Ancestors)

Obstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesPuerperal DisordersUterine HemorrhageHemorrhagePathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Charles Garabedian, MD,PhD

    University Hospital, Lille

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 17, 2019

First Posted

October 21, 2019

Study Start

November 19, 2019

Primary Completion

December 27, 2019

Study Completion

December 27, 2019

Last Updated

July 1, 2020

Record last verified: 2019-10

Locations