NCT04129203

Brief Summary

This is Versi Retriever mechanical thrombectomy device approving study in Japan. Multi center, single arm, prospective registry trial. Physicians control trial, conducted my N Sakai, Kobe City Medical Center General Hospital.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
58

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2019

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2019

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 12, 2019

Completed
7 months until next milestone

First Posted

Study publicly available on registry

October 16, 2019

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2021

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2021

Completed
Last Updated

November 3, 2020

Status Verified

November 1, 2020

Enrollment Period

2.2 years

First QC Date

March 12, 2019

Last Update Submit

November 1, 2020

Conditions

Keywords

acute ischemic stroke

Outcome Measures

Primary Outcomes (1)

  • Good clinical outcome

    modified Rankin Score is 0-2

    90days after procedure

Secondary Outcomes (5)

  • Successful recanalization

    at 3 passes of device in the procedure

  • Successful recanalization

    at end of procedure

  • Symptomatic and asymptomatic intracranial hemorrhage

    at 24 hours after procedure

  • Good clinical outcome 2

    90days after procedure

  • sever advers event

    90days after procedure

Study Arms (1)

Trial arm

EXPERIMENTAL

Mechanical thrombectomy using Versi Retriever

Device: Versi Retriever thrombectomy

Interventions

Mechanical thrombectomy using Versi Retriever

Trial arm

Eligibility Criteria

Age20 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • acute onset neurological sympto m related to occluded vessel
  • within 8 hours from onset to tre atment or within 24 hours from onset to treatment with imaging diagnosis
  • contra-indication or failed to int ravenous rt-PA
  • accessible occlusion at ICA, MC A, VA, BA, PCA
  • of NIHSS
  • of mRS before onset
  • obtain documented informed co ntent

You may not qualify if:

  • following condition; arterial diss ection, engird, inaccessible turtuousity, difficult access by 50% or m ore stenosis, acute intracranial hemorrhage, space occuping lesion or brain tumor, major early ischemic change in brain
  • occlude 2 major vessel territory
  • allege for contrast media,
  • abnormal PTT/APTT within 4 h ours intravenous heparin
  • hemorrhagic tendency or 3 or more INR with Warfarin administration
  • cc or less of Platelet
  • mg/dL or less of blood sugar
  • uncontrolled blood pressure, 185mmHg or more at systolic, 110m mHg or more at diastolic
  • days or less life expancy
  • pregnant or lactating
  • join another trial of medicine or medical device
  • ineligible for trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kobe City Medical Center General Hospital

Kobe, Hyōgo, 650-0047, Japan

RECRUITING

MeSH Terms

Conditions

StrokeIschemic Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Nobuyuki Sakai, MD DMSc

    Kobe City Medical Center General Hospital

    STUDY CHAIR

Central Study Contacts

Nobuyuki Sakai, MD DMSc

CONTACT

Chiaki Sakai, MD PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director, Neurosurgery

Study Record Dates

First Submitted

March 12, 2019

First Posted

October 16, 2019

Study Start

February 1, 2019

Primary Completion

March 31, 2021

Study Completion

December 31, 2021

Last Updated

November 3, 2020

Record last verified: 2020-11

Data Sharing

IPD Sharing
Will not share

Locations