Carotid Duplex Ultrasound for Selecting Patients for Endovascular Thrombectomy in Acute Stroke Patients
ECHO-SELECT
Emergent Carotid Ultrasound in Hyperacute Cerebral Vessel Occlusion for Selecting Patients to be Treated With Endovascular Clot Retrieval Treatment
1 other identifier
interventional
40
1 country
1
Brief Summary
The aim of this study is to address the usefulness of carotid duplex ultrasound as vascular imaging for selecting acute stroke patients for endovascular thrombectomy.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Oct 2016
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2016
CompletedFirst Submitted
Initial submission to the registry
December 8, 2016
CompletedFirst Posted
Study publicly available on registry
December 12, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 30, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
October 30, 2019
CompletedFebruary 20, 2020
February 1, 2020
2.7 years
December 8, 2016
February 18, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
modified Rankin Scale
at 90 days after onset
Study Arms (1)
carotid duplex ultrasound
EXPERIMENTALSingle arm study. After detection of occluded vessels by vascular imaging using carotid duplex ultrasound, digital subtraction angiography is immediately performed before acute endovascular treatment.
Interventions
When the ratio of the end diastolic velocity in the common carotid arteries is greater than 1.4 or the diastolic flow in the internal carotid artery is not detected by vascular imaging using carotid duplex ultrasound, digital subtraction angiography is immediately performed before acute endovascular treatment. If vessel occlusion is not detected by carotid duplex ultrasound, additional vascular imaging including MR angiography or CT angiography is considered.
Eligibility Criteria
You may qualify if:
- Endovascular treatment can be initiated within 6 hours of symptom onset.
- ASPECTS of \>=6 is diagnosed by two or more stroke physicians.
- The end diastolic velocity in the common carotid arteries or internal carotid artery is evaluated by carotid duplex ultrasound
- NIHSS score of \>=6.
- Age\>=18 years.
- Written informed consent is obtained.
You may not qualify if:
- Pre-stroke modified Rankin Scale (mRS) score \>=2.
- Difficulties to evaluate ASPECTS on initial CT.
- Difficulties to groin puncture.
- History of severe allergic reaction to contrast medium.
- End stage renal disease.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Ryo Itabashilead
Study Sites (1)
Kohnan hospital
Sendai, Miyagi, 9828523, Japan
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Ryo Itabashi, MD
Kohnan Hospital
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Department chair of Stroke Neurology
Study Record Dates
First Submitted
December 8, 2016
First Posted
December 12, 2016
Study Start
October 1, 2016
Primary Completion
June 30, 2019
Study Completion
October 30, 2019
Last Updated
February 20, 2020
Record last verified: 2020-02