NCT04127331

Brief Summary

The primary objective of this study is to evaluate gastric volume and contents as well as gall bladder size in patients scheduled for routine, urgent, and emergency surgery. The hypothesis is that patients with stress, pain and opioid administration will have delayed gastric emptying and therefore a larger gastric fluid volume than those scheduled for elective surgery. The patients who have an appropriate NPO time will have a larger gallbladder size than the patients with shorter NPO time.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable surgery

Timeline
Completed

Started Jan 2020

Typical duration for not_applicable surgery

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 14, 2019

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 15, 2019

Completed
3 months until next milestone

Study Start

First participant enrolled

January 10, 2020

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 6, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 6, 2022

Completed
1.2 years until next milestone

Results Posted

Study results publicly available

November 21, 2023

Completed
Last Updated

November 21, 2023

Status Verified

February 1, 2023

Enrollment Period

2.7 years

First QC Date

October 14, 2019

Results QC Date

February 9, 2023

Last Update Submit

February 9, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Aspiration Risk Grade

    Grade 0: No fluid visible in the gastric antrum Grade 1: Clear fluid visualized with volume \< 1.5 mL/kg Grade 2: Clear fluid visualized with volume \> 1.5 mL/kg (High risk of aspiration)

    Baseline

Secondary Outcomes (3)

  • NPO at the Time of Injury

    Baseline

  • NPO at the Time of Surgery

    Baseline

  • Pre-operative Opioid Administration

    Baseline

Study Arms (3)

Routine

ACTIVE COMPARATOR

Patients who are scheduled for routine outpatient surgery.

Device: Point-of-Care Ultrasound

Urgent

ACTIVE COMPARATOR

Patients who are scheduled for urgent surgery.

Device: Point-of-Care Ultrasound

Emergent

ACTIVE COMPARATOR

Patients who are scheduled for emergency surgery.

Device: Point-of-Care Ultrasound

Interventions

Portable ultrasonography done at the bedside.

EmergentRoutineUrgent

Eligibility Criteria

Age2 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • ASA 1-3 patients aged 2-18 years of scheduled for elective, urgent, or emergent surgery under general anesthesia.

You may not qualify if:

  • History of upper gastro-intestinal surgery.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Nationwide Children's Hospital

Columbus, Ohio, 43205, United States

Location

Results Point of Contact

Title
Dr. Alok Moharir
Organization
Nationwide Children's Hospital

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Clinical Assistant Professor of Anesthesiology

Study Record Dates

First Submitted

October 14, 2019

First Posted

October 15, 2019

Study Start

January 10, 2020

Primary Completion

September 6, 2022

Study Completion

September 6, 2022

Last Updated

November 21, 2023

Results First Posted

November 21, 2023

Record last verified: 2023-02

Data Sharing

IPD Sharing
Will not share

Locations