NCT04118062|Completed
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Sponsor study identifier
interventional
128
1 country
1
Study Start
February 2, 2021
Actual (reported)Primary Completion
May 26, 2023
Actual (reported)Study Completion
May 26, 2024
Actual (reported)Resistance to treatment is one of the major themes in cancer research. Despite this, the definition and clinical implications of resistance to treatment remain under-explored, and patient-physician communication in this context still constitutes a challenge. When resistance to cancer treatments occurs, physicians not only have to explain to the patient the phenomenon of resistance, often based on complex results (biological results, genomic tests, imaging, etc.), but also need to offer alternative therapies, whilst fostering shared medical decision-making. These different tasks are particularly challenging for clinicians, especially since there are large individual differences at patient level. Indeed, each patient has his or her own unique information needs, capacity for understanding, and level of desire to participate in treatment decisions.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 26, 2024
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 11, 2019
Actual (reported)October 7, 2019
Actual (reported)February 2, 2021
Actual (reported)May 26, 2023
Actual (reported)May 26, 2024
Actual (reported)List of patients' needs, particularly regarding communication with physicians
List of patients' needs in support, and information delivered by physicians in consultation
18 months
Items of communication booklet
Number and content of items, number of categories / themes,
18 months
Acceptability of the booklet evaluated
Items and issues revised and reformulated by the experts. Application of the booklet in the determined clinic: Modes of administration of the booklet and patients concerned identified. Implementation of the tool and relevant patients identified
18 months
Content of communication booklet validated
Consensus criteria: Consensus can be considered to have been reached if the majority of participants (70% or more) rank an item similarly
Questionnaires and semi-structured individual interviews with patients with Metastatic Uveal Melanoma
Questionnaires and semi-structured individual interviews with patients with Triple Negative Breast Cancer
Questionnaires
Institut Curie
Paris, 75005, France
Rault A, Dolbeault S, Terrasson J, Bouleuc C, Cottu P, Piperno-Neumann S, Rodrigues M, Vaflard P, Bredart A. Facilitating patient-oncologist communication in advanced treatment-resistant cancer: development and feasibility testing of a question prompt list. Pilot Feasibility Stud. 2024 Aug 28;10(1):116. doi: 10.1186/s40814-024-01543-y.
Bredart A, Rault A, Terrasson J, Seigneur E, De Koning L, Hess E, Savignoni A, Cottu P, Pierga JY, Piperno-Neumann S, Rodrigues M, Bouleuc C, Dolbeault S. Helping Patients Communicate With Oncologists When Cancer Treatment Resistance Occurs to Develop, Test, and Implement a Patient Communication Aid: Sequential Collaborative Mixed Methods Study. JMIR Res Protoc. 2022 Jan 12;11(1):e26414. doi: 10.2196/26414.
Sylvie DOLBEAULT, PHD
Institut Curie
Anne BREDART, PHD
Institut Curie
128 participants (actual enrollment reported by the registry).
First Submitted
September 11, 2019
Early Detection of Mental Disorders in Adolescents With Chronic Pain: Creation of a Screening Tool for Use by the General Practitioner
18 months
Questionnaires and semi-structured individual interviews with patients with Luminal B Breast Cancer
Questionnaires and semi-structured individual interviews with parents of children with cancer.
Focus groups (or group interviews) and DELPHI consensus method with expert patients
Focus groups (or group interviews) and DELPHI consensus method with Researchers and Clinicians
Semi-structured individual interviews
Focus Group
DELPHI Consensus Method
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
First Posted
October 7, 2019
Study Start
February 2, 2021
Actual (reported)Primary Completion
May 26, 2023
Actual (reported)Study Completion
May 26, 2024
Actual (reported)Last Updated
September 19, 2025
Record last verified: 2025-09
Investigators will share de-identified data sets with interested reserachers, educators or clincians. Materials generated under the project will be disseminated in accordance with Institut Curie policies.
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Source: ClinicalTrials.gov.
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