Key Insights

Highlights

Success Rate

62% trial completion

Published Results

63 trials with published results (14%)

Research Maturity

102 completed trials (23% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

13.8%

62 terminated out of 449 trials

Success Rate

62.2%

-24.3% vs benchmark

Late-Stage Pipeline

8%

37 trials in Phase 3/4

Results Transparency

62%

63 of 102 completed with results

Key Signals

63 with results62% success62 terminated

Data Visualizations

Phase Distribution

401Total
Not Applicable (22)
Early P 1 (11)
P 1 (185)
P 2 (146)
P 3 (34)
P 4 (3)

Trial Status

Recruiting123
Completed102
Terminated62
Active Not Recruiting55
Unknown53
Not Yet Recruiting28

Trial Success Rate

62.2%

Benchmark: 86.5%

Based on 102 completed trials

Clinical Trials (449)

Showing 20 of 20 trials
NCT04771871Phase 2RecruitingPrimary

MicroRNA Profiles in Triple Negative Breast Cancer

NCT07300475Phase 1Not Yet RecruitingPrimary

Cancer Immunotherapeutic (PCI) Strategy in Triple Negative Breast Cancer Patients

NCT06845319Phase 2RecruitingPrimary

NeoCARD: Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Triple-Negative Breast Cancer Patients

NCT04331067Phase 1Active Not RecruitingPrimary

Neoadjuvant Nivolumab and Chemotherapy in Patients With Localized Triple-negative Breast Cancer

NCT04434040Phase 2Recruiting

Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

NCT03797326Phase 2Completed

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)

NCT07332975RecruitingPrimary

ctDNA Positive Patients Diagnosed With cT1bN0 and cT1cN0 TNBC

NCT06224673Phase 2Not Yet Recruiting

ARX788 for Treating Patients With HER2-low Locally Advanced Unresectable or Metastatic Breast Cancer

NCT07134556Phase 2WithdrawnPrimary

Phase II Trial Evaluating the Safety and Efficacy of the Combination of Zimberelimab, Domvanalimab and Sacituzumab Govitecan as 1L Therapy for PD-L1 Positive Advanced TNBC

NCT05633654Phase 3RecruitingPrimary

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

NCT04468061Phase 2Recruiting

Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

NCT07261631Phase 1Recruiting

Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors

NCT05645380Phase 2Active Not RecruitingPrimary

Neoadjuvant TIL- and Response-Adapted Chemoimmunotherapy for TNBC

NCT02734290Phase 1Active Not RecruitingPrimary

Standard of Care Chemotherapy Plus Pembrolizumab for Breast Cancer

NCT06562192Phase 1Recruiting

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

NCT03756298Phase 2Active Not RecruitingPrimary

Efficacy and Safety of Atezolizumab Plus Capecitabine Adjuvant Therapy for Triple Receptor-Negative Breast Cancer

NCT07115043Phase 1Recruiting

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

NCT06889688Phase 3Recruiting

Phase III Trial of Camrelizumab+Apatinib+Eribulin vs. Physician's Choice Chemotherapy in Advanced Triple-Negative Breast Cancer

NCT04595565Phase 3Active Not Recruiting

Sacituzumab Govitecan in Primary HER2-negative Breast Cancer

NCT06347068Phase 1Recruiting

Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells

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