Antibiotic Adherence Practices in Dermatologic Surgery

NCT04117724 | Completed

• 1 other identifier: 833525
• Study Type: observational
• Target: 276
• Locations: 1 country
• Sites: 9

Brief Summary

This multi-center prospective observational cohort study will examine the prevalence of non-adherence along with analyze the risk factors of non-adherence for patients presenting to dermatologic surgery. Patients prescribed antibiotics will be invited to participate in the study and appropriate follow up to inquire about antibiotic usage will be conducted. All data will be collected and stored in a secured REDCap database managed by the Penn Dermatologic Surgery Clinical Research Team.

Conditions

Medication Adherence

Outcome Measures

Primary Outcomes (1)

• Rate of antibiotic non-adherence

  To analyze the prevalence of antibiotic non-adherence in the dermatologic surgery setting

  Oct 3 2019-July 1 2021

Secondary Outcomes (1)

• Risk factors for antibiotic non-adherence

  Oct 3 2019-July 1 2021

Interventions

Survey OTHER

Patients will be asked to complete a 4 question survey assessing adherence. Follow up via patient's preferred method of contact will be conducted after the patient's intended antibiotic completion date and covariates for antibiotic regimens will be recorded including antibiotic type, number of doses, antibiotic duration, reason for non-adherence, pills remaining, and number of other medications.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

We plan to examine patients who have presented to a dermatologic surgery clinic and were prescribed post-operative antibiotics from June 1, 2019 to June 1, 2021 at the University of Pennsylvania Health System and other IRB approved sites.

You may qualify if:

• Age greater than equal to 18
• All patients presenting to one of the dermatologic surgery settings approved by the IRB who are prescribed a post-operative antibiotic regimen

You may not qualify if:

• Patients who do not present to or are not prescribed post-operative antibiotics in a dermatologic surgery setting

Sponsors & Collaborators

• University of Pennsylvania: lead

Study Sites (9)

University of California, Davis

Davis, California, 95616, United States

Location

Indiana University

Indianapolis, Indiana, 46202, United States

Location

University of Minnesota

Minneapolis, Minnesota, 55455, United States

Location

University of Missouri Health Care

Columbia, Missouri, 65201, United States

Location

Washington University in St. Louis

St Louis, Missouri, 63130, United States

Location

The Ohio State University

Columbus, Ohio, 43230, United States

Location

Oregon Health & Science University

Portland, Oregon, 97239, United States

Location

Penn State Health Milton S. Hershey Medical Center

Hershey, Pennsylvania, 17033, United States

Location

UT Southwestern Medical Center

Dallas, Texas, 75390, United States

Location

Related Publications (6)

• Bae-Harboe YS, Liang CA. Perioperative antibiotic use of dermatologic surgeons in 2012. Dermatol Surg. 2013 Nov;39(11):1592-601. doi: 10.1111/dsu.12272. Epub 2013 Jul 18.

  PMID: 23865410 BACKGROUND

• Barbieri JS, Etzkorn JR, Margolis DJ. Use of Antibiotics for Dermatologic Procedures From 2008 to 2016. JAMA Dermatol. 2019 Apr 1;155(4):465-470. doi: 10.1001/jamadermatol.2019.0152.

  PMID: 30825412 BACKGROUND

• Kardas P. Patient compliance with antibiotic treatment for respiratory tract infections. J Antimicrob Chemother. 2002 Jun;49(6):897-903. doi: 10.1093/jac/dkf046.

  PMID: 12039881 BACKGROUND

• Pechere JC. Parameters important in short antibiotic courses. J Int Med Res. 2000;28 Suppl 1:3A-12A.

  PMID: 11092225 BACKGROUND

• Pechere JC. Patients' interviews and misuse of antibiotics. Clin Infect Dis. 2001 Sep 15;33 Suppl 3:S170-3. doi: 10.1086/321844.

  PMID: 11524715 BACKGROUND

• Sclar DA, Tartaglione TA, Fine MJ. Overview of issues related to medical compliance with implications for the outpatient management of infectious diseases. Infect Agents Dis. 1994 Oct;3(5):266-73.

  PMID: 7866659 BACKGROUND

MeSH Terms

Conditions

Medication Adherence

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Patient Compliance; Patient Acceptance of Health Care; Treatment Adherence and Compliance; Health Behavior; Behavior

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 3, 2019
• First Posted: October 7, 2019
• Study Start: October 10, 2019
• Primary Completion: May 1, 2021
• Study Completion: May 1, 2021
• Last Updated: August 30, 2021

Record last verified: 2021-08

Data Sharing

• IPD Sharing: Will not share

Locations

US (9)