NCT04108754|Completed
Small-vessel Disease Burden and Early Risk of Stroke After Transient Ischemic Attack
TIA
Loading search results
TIA
Sponsor study identifier
observational
376
1 country
1
Study Start
August 1, 2018
Actual (reported)Primary Completion
August 1, 2018
Actual (reported)Study Completion
December 1, 2018
Actual (reported)Predicting the risk of stroke remains a challenge in the management of transient ischemic attack (TIA). In addition to clinical variables, morphological features such as the presence of a diffusion weighted sequence (DWI) lesion and carotid stenosis of at least 50% improve risk stratification and are considered in the literature. score ABCD3-I1. Several studies have shown that brain microhemorrhages are associated with the risk of early stroke in patients with TIA. Data on white matter hypersignals on the T2-weighted sequence or FLAIR (FLuid Attenuated Inversion Recovery) are more conflicting. The global microangiopathic load, including the gaps, the hypersignals of the white matter, the perivascular spaces visible on MRI in the basal ganglia, especially when they are very numerous (\> 20) and the gaps, have recently been described as being associated with stroke risk within 2 to 3 years of TIA or ischemic stroke. To date, the predictive value of global microangiopathic burden on early stroke risk in the course of TIA is not known.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 1, 2018
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
August 1, 2018
Actual (reported)August 1, 2018
Actual (reported)December 1, 2018
Actual (reported)September 26, 2019
Actual (reported)September 30, 2019
Actual (reported)stroke recurrence within 90 days,
The stroke recurrence within 90 days is determined via a clinical consultation or telephone call to the patient with a structured questionnaire.
90 days
Patients in the neurovascular unit of the Neurological Hospital of Lyon between 01/01/2016 and 30/12/2017 with a probable diagnosis of AIT and having an MRI within 7 days of TIA.
to determine the value of the global microangiopathic burden on the prediction of early stroke risk in a homogeneous cohort of TIA.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
All patients in the neurovascular unit of the Neurological Hospital of Lyon between 01/01/2016 and 30/12/2017 with a probable diagnosis of TIA and having an MRI within 7 days of the TIA.
Hospices Civils de Lyon
Bron, 69677, France
Norbert NIGHOGHOSSIAN
Hospices Civils de Lyon
376 participants (actual enrollment reported by the registry).
First Submitted
September 26, 2019
First Posted
September 30, 2019
Study Start
August 1, 2018
Actual (reported)Aortic Dissection With 4-dimensional Phase-contrast Magnetic Resonance Imaging
Contact the study team to confirm eligibility.
Primary Completion
August 1, 2018
Actual (reported)Study Completion
December 1, 2018
Actual (reported)Last Updated
September 30, 2019
Record last verified: 2019-09
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: