the Study of Persistent Organic Pollutants in Human Milk

NCT04102085 | Unknown

• 1 other identifier: DH/SEB/NCD/18/2018-19
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The study aims to recruit eligible participants and conduct interviews, collect human milk samples, and conduct laboratory analysis of persistent organic pollutants' levels in human milk samples.

Conditions

Breast Milk Collection

Outcome Measures

Primary Outcomes (1)

• Amount of persistent organic pollutants in breast milk

  Approximately 30 types of persistent organic pollutants will be tested

  2 years

Study Arms (1)

Mothers under 30

no intervention will be administered

Other: no intervention

Interventions

no intervention OTHER

no intervention

Mothers under 30

Eligibility Criteria

• Age: Up to 30 Years
• Gender Eligibility Details: Primiparae
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Fifty eligible participants (nursing mothers) will be identified during their postnatal visits at four selected Maternal Child Health Centres (MCHCs) of the Department of Health, representing four major regions in Hong Kong: Sai Ying Pun MCHC (Hong Kong Island); Kowloon City MCHC (Kowloon); Madam Yung Fung Shee MCHC (New Territories West); and Ma On Shan MCHC (New Territories East). If the recruitment is unsatisfactory in the above four centres, other MCHCs will be involved.

You may qualify if:

• Primiparae;
• years of age or below;
• Have normal pregnancy;
• Breastfeeding one infant only, and not multiple pregnancy;
• Resided in Hong Kong for at least 10 years immediately before the date of interview;
• Available for sample collection within 3 to 8 weeks of delivery; and
• Both mother and child should be apparently healthy and free from any known infectious or other diseases (e.g. clinical hepatitis, AIDs, HIV).

You may not qualify if:

• participants with previously diagnosed major diseases such as hepatitis, AIDS and other such diseases shall be excluded from the study

Sponsors & Collaborators

• Chinese University of Hong Kong: lead

Study Sites (1)

Bonnie Kwok

Hong Kong, 000, Hong Kong

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

Breast milk

MeSH Terms

Conditions

Breast Milk Expression

Condition Hierarchy (Ancestors)

Breast Feeding; Feeding Behavior; Behavior

Study Officials

• Lap Ah Tse

  Chinese University of Hong Kong

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Bonnie Kwok

CONTACT

22528795; bonniekwokhl@cuhk.edu.hk

Lap Ah Tse

CONTACT

22528791; shelly@cuhk.edu.hk

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor

Study Record Dates

• First Submitted: September 23, 2019
• First Posted: September 25, 2019
• Study Start: September 25, 2019
• Primary Completion: September 25, 2021
• Study Completion: October 25, 2021
• Last Updated: December 16, 2020

Record last verified: 2020-12

Data Sharing

• IPD Sharing: Will not share

Locations

HK (1)