The Muti-centered Investigation，Pathogenesis and Intervention Study of Non-suicidal Self-injury Behavior in China
1 other identifier
interventional
100
1 country
1
Brief Summary
Non-suicidal self-injury (NSSINSSINSSI) refers to a series of direct and consequently repeated injuries to one's body without suicidal intent. At present, it has become an important issue of mental disorders. This study is expected to complete a multi-center epidemiological survey of non-suicidal self-injury in China, and to study its pathogenesis and intervention methods.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Sep 2019
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 4, 2019
CompletedStudy Start
First participant enrolled
September 10, 2019
CompletedFirst Posted
Study publicly available on registry
September 19, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 31, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
June 30, 2022
CompletedApril 27, 2020
April 1, 2020
2.4 years
September 4, 2019
April 23, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
Self-made Behavior Report Scale
Self reported non-suicidal self-injury behaviors over the past 2 weeks. Each item is scored 0-3(0=never; 3=every day), yielding a total between 0 and 6, also need choose locations of injury(such as hand, arm and so on. )
2 weeks
Study Arms (2)
NSSI-DBT
EXPERIMENTALDialectical behavior therapy, 2 hours every week for 13 weeks.
NSSI-SSGT
ACTIVE COMPARATORSocial support group therapy, 2 hours every week for 13 weeks.
Interventions
15 patients in a group are treated by 2 psychotherapist by DBT including mindfulness skills, distress tolerance skills, emotional regulation skills and interpersonal effectiveness skills.
15 patients in a group are treated by 2 psychotherapist by SSGT.(Giving support to each other.)
Eligibility Criteria
You may qualify if:
- years old;
- Voluntary participation, signing informed consent and obtaining the consent of family members of patients under 18 years old;
You may not qualify if:
- history and family of neurological or psychiatric disorders;
- history of psychiatric disorders and family history;
- severe somatic diseases;
- taking psychotropic drugs within three months;
- pregnancy and lactation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Nanjing Brain Hospital
Nanjing, Jiangsu, 210029, China
Related Publications (1)
Lang AN, Zhong Y, Lei W, Xiao Y, Hang Y, Xie Y, Lv Z, Zhang Y, Liu X, Liang M, Zhang C, Zhang P, Yang H, Wu Y, Wang Q, Yang K, Long J, Liu Y, Wang S, Tang Y, Lei M, Zhang D, Ouyang L, Zhang L, Wang C. Neural mechanism of non-adaptive cognitive emotion regulation in patients with non-suicidal self-injury. Compr Psychiatry. 2024 Aug;133:152487. doi: 10.1016/j.comppsych.2024.152487. Epub 2024 May 1.
PMID: 38714144DERIVED
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate chief physician
Study Record Dates
First Submitted
September 4, 2019
First Posted
September 19, 2019
Study Start
September 10, 2019
Primary Completion
January 31, 2022
Study Completion
June 30, 2022
Last Updated
April 27, 2020
Record last verified: 2020-04