Prevelance of Keratoconus
1 other identifier
observational
300
0 countries
N/A
Brief Summary
Keratoconus is a degenerative disease entity characterized by conical shape ectasia of the cornea. progressive conical deformation of the cornea leads to substantial astigmatism. Patients who are at an advanced stage of ectasia are often led to corneal transplant or other treatments, which essentially aim at correcting the refractive error and not in treating the ectasia. The top of the protruding cone that corneal configuration may be close to the visual axis or below and nasal of that. The disease manifests during adolescence, followed by slow progressive course, although it is possible to stabilize anytime. In 85% of cases both eyes are affected, but the severity of the attack can present significant asymmetry.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Oct 2019
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 15, 2019
CompletedFirst Posted
Study publicly available on registry
September 17, 2019
CompletedStudy Start
First participant enrolled
October 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2021
CompletedSeptember 17, 2019
September 1, 2019
1 year
September 15, 2019
September 15, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
Prevalence of keratoconus in different areas in assiut
Number of keratoconus cases detected areas in indivduals attending refractive surgery centers in Assiut
one year
Study Arms (1)
patients with keratoconus
patients with keratoconus attending refractive surgery centers in Assiut will be subjected to the following :- 1. Full history and clinical evaluation. 2. collection of individual data ( residency , occupation , special habbit , chronic illness ) 3. Analysis of results to assess prevelance of keratoconus and its distribution geographically in Assiut
Interventions
opthalmologic examination : Refraction Best corrected visual acuity Intraocular pressure Slit lamp examination
Eligibility Criteria
patients with keratoconus in people attending refractive surgery
You may qualify if:
- persons attending refractive surgery centers in Asssiut.
- patients found to have keratoconus are included , based on history , clinical examination and corneal topography
You may not qualify if:
- patients not attending those refractive surgery centers.
- patients attending these centers but not diagnosed to be keratoconus .
- Pregnancy or breastfeeding
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Jonas JB, Nangia V, Matin A, Kulkarni M, Bhojwani K. Prevalence and associations of keratoconus in rural maharashtra in central India: the central India eye and medical study. Am J Ophthalmol. 2009 Nov;148(5):760-5. doi: 10.1016/j.ajo.2009.06.024. Epub 2009 Aug 11.
PMID: 19674732BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- principal investigator
Study Record Dates
First Submitted
September 15, 2019
First Posted
September 17, 2019
Study Start
October 1, 2019
Primary Completion
October 1, 2020
Study Completion
October 1, 2021
Last Updated
September 17, 2019
Record last verified: 2019-09