Surveillance of Community-Associated MRSA
1 other identifier
observational
50
1 country
1
Brief Summary
The purpose of this study is to obtain information from patients diagnosed with a skin and soft tissue infection (also known as an abscess or 'boil' or 'rising') and determine whether or not MRSA is present in the child's different surface skin areas or nose. We also plan to compare how these infections look in the lab, by identifying in detail parts of the germ that caused the infection or is found on the skin/nose areas
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Jul 2019
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 14, 2019
CompletedFirst Submitted
Initial submission to the registry
August 29, 2019
CompletedFirst Posted
Study publicly available on registry
September 10, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 8, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
July 8, 2020
CompletedSeptember 10, 2019
September 1, 2019
12 months
August 29, 2019
September 5, 2019
Conditions
Outcome Measures
Primary Outcomes (2)
Number of children with MRSA and MSSA carriage
We are measuring this by swabbing 5 locations on the body of each study participant. We are swabbing the anterior nares (nostrils), under both axilla (armpits), oropharyngeal area (mouth), skin around the perirectal area, and the actual abscess wound.
1 year
Number of children with MRSA and MSSA skin and soft tissue infections
We are measuring this by collecting wound cultures from all children who present with skin and soft issue infections.
1 year
Secondary Outcomes (2)
Number of strains of MRSA and MSSA with unique genomic sequences
1 year
Percent relatedness between MRSA and MSSA protein profiles
1 year
Eligibility Criteria
Children's is the largest pediatric clinical care provider in the country. Currently, across the three hospitals (Hughes Spalding, Egleston, and Scottish Rite), there are 561 licensed beds. In 2013, CHOA managed more than 860,849 patient visits, with over 218,231 Emergency Department visits. Enrolled patients will be tested for colonization by CA-MRSA and CA-MSSA by standard swabbing of specified sites (nares, axilla, oropharyngeal, and perirectal areas). A culture swab will also be taken of an enrolled patient's wound infection (skin and soft tissue infection).
You may qualify if:
- Diagnosis of skin and soft tissue infections (abscesses and cellulitis)
- Patient aged \>6 months and \<21 years
You may not qualify if:
- Currently on antibiotics
- Unimmunized patients
- Pertinent co-morbid conditions (immune deficiency, underlying cardiac, skin, GI disorder)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Children's Healthcare of Atlanta
Atlanta, Georgia, 30342, United States
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Pediatric Infectious Disease Specialist
Study Record Dates
First Submitted
August 29, 2019
First Posted
September 10, 2019
Study Start
July 14, 2019
Primary Completion
July 8, 2020
Study Completion
July 8, 2020
Last Updated
September 10, 2019
Record last verified: 2019-09