Healthy Hip Study: Conservative Management for Pre-arthritic Hip Disorders

NCT04069507 | Completed

• 2 other identifiers: 2018071501K23AR074520-01A1
• Study Type: observational
• Target: 88
• Locations: 1 country
• Sites: 1

Brief Summary

Pre-arthritic hip disorders can cause pain, interfere with daily activities and exercise, and lead to the development of osteoarthritis in young adults. Surgical and conservative treatment options are being developed and studied, but it is currently unclear why some patients improve with a particular treatment plan while others do not. The goal of this research project is to develop a tool that predicts which combination of treatment options will be most effective for each individual patient.

Conditions

Femoroacetabular Impingement; Acetabular Dysplasia; Acetabular Labrum Tear; Hip Pain; Rehabilitation

Keywords

Biopsychosocial health; Clinical prediction tool; Patient-reported outcomes; Movement pattern training

Outcome Measures

Primary Outcomes (1)

• Rate of successful conservative management

  Percentage of participants who self-report satisfactory overall hip symptoms and no plan to proceed with surgery. The rate will be adjusted for patients' baseline demographics, severity of hip symptoms, biopsychosocial profile, hypermobility profile, movement and activity patterns, and hip anatomy.

  1 Year

Secondary Outcomes (2)

• Rate of adherence and symptom response to movement pattern training

  12 Weeks

• Rate of clinically meaningful improvement with conservative management

  1 Year

Eligibility Criteria

• Age: 15 Years - 40 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Participants will be recruited from patients who present to a single tertiary care academic orthopedic department. Potentially eligible patients will have presented to an orthopedic surgeon or sports medicine physiatrist for a new evaluation of hip pain.

You may qualify if:

• Clinically suspected intra-articular hip joint pain
• One or more of the following radiographic/MRI findings: Femoroacetabular impingement, acetabular dysplasia, acetabular labral tear, acetabular retroversion, femoral anteversion, hip microinstability, and/or normal radiographs

You may not qualify if:

• Surgery recommended and/or scheduled at initial clinic evaluation
• "At-risk" acetabular dysplasia (Lateral center edge angle \< 15 degrees)
• Other intra-articular hip diagnoses including: Slipped capital femoral epiphysis, Legg-Calve-Perthes disease, Avascular necrosis
• Moderate or severe hip osteoarthritis (Tonnis grade 2 or 3)
• Hip/pelvis weakness from brain/nerve disorder (Ex: lumbosacral radiculopathy with weakness, cerebral palsy)
• Previous same-side hip surgery, hip fracture, hip infection, and/or hip tumor
• Inflammatory arthropathy
• Known pregnancy

Sponsors & Collaborators

• Washington University School of Medicine: lead
• National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS): collaborator

Study Sites (1)

Washington University School of Medicine

St Louis, Missouri, 63110, United States

Location

Related Publications (7)

• Harris-Hayes M, Czuppon S, Van Dillen LR, Steger-May K, Sahrmann S, Schootman M, Salsich GB, Clohisy JC, Mueller MJ. Movement-Pattern Training to Improve Function in People With Chronic Hip Joint Pain: A Feasibility Randomized Clinical Trial. J Orthop Sports Phys Ther. 2016 Jun;46(6):452-61. doi: 10.2519/jospt.2016.6279. Epub 2016 Apr 26.

  PMID: 27117727 BACKGROUND

• Prather H, Creighton A, Sorenson C, Simpson S, Reese M, Hunt D, Rho M. Anxiety and Insomnia in Young and Middle-Aged Adult Hip Pain Patients With and Without Femoroacetabular Impingement and Developmental Hip Dysplasia. PM R. 2018 May;10(5):455-461. doi: 10.1016/j.pmrj.2017.10.007. Epub 2017 Oct 27.

  PMID: 29111466 BACKGROUND

• Hunt D, Prather H, Harris Hayes M, Clohisy JC. Clinical outcomes analysis of conservative and surgical treatment of patients with clinical indications of prearthritic, intra-articular hip disorders. PM R. 2012 Jul;4(7):479-87. doi: 10.1016/j.pmrj.2012.03.012. Epub 2012 May 16.

  PMID: 22595328 BACKGROUND

• Prather H, Decker G, Bonnette M, Simpson S, Hunt D, Sahrmann S, Cheng A, Nepple J. Hip Radiograph Findings in Patients Aged 40 Years and Under with Posterior Pelvic Pain. PM R. 2019 Aug;11 Suppl 1:S46-S53. doi: 10.1002/pmrj.12180. Epub 2019 Jul 25.

  PMID: 31059595 BACKGROUND

• Prather H, Cheng A, Steger-May K, Maheshwari V, VanDillen L. Association of Hip Radiograph Findings With Pain and Function in Patients Presenting With Low Back Pain. PM R. 2018 Jan;10(1):11-18. doi: 10.1016/j.pmrj.2017.06.003. Epub 2017 Jun 16.

  PMID: 28629805 BACKGROUND

• Prather H, Cheng A, Steger-May K, Maheshwari V, Van Dillen L. Hip and Lumbar Spine Physical Examination Findings in People Presenting With Low Back Pain, With or Without Lower Extremity Pain. J Orthop Sports Phys Ther. 2017 Mar;47(3):163-172. doi: 10.2519/jospt.2017.6567. Epub 2017 Feb 3.

  PMID: 28158964 BACKGROUND

• Cheng AL, Pashos MM, Hannemann AJ, Brady BK, Huecker JB, Steger-May K, Prather H, Clohisy JC, Harris-Hayes M. Predictors and rate of satisfactory response to nonoperative management for nonarthritic hip-related pain. PM R. 2026 Jan 27. doi: 10.1002/pmrj.70085. Online ahead of print.

  PMID: 41589432 DERIVED

MeSH Terms

Conditions

Femoracetabular Impingement; Hip Dislocation

Condition Hierarchy (Ancestors)

Joint Diseases; Musculoskeletal Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Joint Dislocations; Wounds and Injuries; Hip Injuries

Study Officials

• Abby L Cheng, MD

  Washington University School of Medicine

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: August 21, 2019
• First Posted: August 28, 2019
• Study Start: October 15, 2019
• Primary Completion: September 22, 2023
• Study Completion: September 22, 2024
• Last Updated: March 28, 2025

Record last verified: 2025-03

Locations

US (1)