NCT04063657

Brief Summary

Aim:

  • Determine if external fixation decreases soft tissue complications compared to splinting.
  • Determine if external fixation decreases time to definitive surgical stabilization and improves final fixation compared to splinting.
  • Determine if external fixation improves functional outcomes as evaluated by validated functional scoring systems. Hypothesis:
  • External fixation improves definitive fixation and functional outcomes of acute calcaneal fractures with decreased complication rates compared to splinting

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 14, 2019

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

August 7, 2019

Completed
14 days until next milestone

First Posted

Study publicly available on registry

August 21, 2019

Completed
13 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 3, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 3, 2019

Completed
2.4 years until next milestone

Results Posted

Study results publicly available

February 9, 2022

Completed
Last Updated

February 9, 2022

Status Verified

January 1, 2022

Enrollment Period

3 months

First QC Date

August 7, 2019

Results QC Date

January 12, 2022

Last Update Submit

January 12, 2022

Conditions

Keywords

Staged External FixationSplintingSoft tissue complications

Outcome Measures

Primary Outcomes (7)

  • Time to Definitive Surgery

    Duration of time from injury to definitive surgery

    Within 2 weeks from injury

  • Soft Tissue Complications

    Incidence of infection, dehiscence and need for soft tissue coverage

    Assessed at 2 weeks after surgery

  • Soft Tissue Complications

    Incidence of infection, dehiscence and need for soft tissue coverage

    Assessed at 6 weeks after surgery

  • Soft Tissue Complications

    Incidence of infection, dehiscence and need for soft tissue coverage

    Assessed at 12 weeks after surgery

  • Soft Tissue Complications

    Incidence of infection, dehiscence and need for soft tissue coverage

    Assessed at 6 months after surgery

  • Soft Tissue Complications

    Incidence of infection, dehiscence and need for soft tissue coverage

    Assessed at 12 months after surgery

  • Soft Tissue Complications

    Incidence of infection, dehiscence and need for soft tissue coverage

    Assessed at 24 months after surgery

Secondary Outcomes (10)

  • Union Rate

    Plain xrays at 6 weeks, 12 weeks, 6 months, 1 year, and 2 years after surgery. CT scan at 1 year.

  • Radiographic Parameters - Bohler's Angle

    Assessed at 2, 6, & 12 weeks, and 6, 12, & 24 months after surgery

  • Radiographic Parameters - Calcaneal Height

    Assessed at 2, 6, & 12 weeks, and 6, 12, & 24 months after surgery

  • Radiographic Parameters - Angle of Gissan

    Assessed at 2, 6, & 12 weeks, and 6, 12, & 24 months after surgery

  • Radiographic Parameters - Calcaneal Width

    Assessed at 2, 6, & 12 weeks, and 6, 12, & 24 months after surgery

  • +5 more secondary outcomes

Study Arms (2)

External fixation

ACTIVE COMPARATOR

Adults diagnosed with an acute (\<2 days from injury) calcaneal fracture recommended for operative treatment will be placed in external fixator until the patient is deemed clinically appropriate for definitive surgical fixation.

Procedure: External fixator

Splinting

ACTIVE COMPARATOR

Adults diagnosed with an acute (\<2 days from injury) calcaneal fracture recommended for operative treatment will be placed in a short leg splint until the patient is deemed clinically appropriate for definitive surgical fixation.

Procedure: Splinting

Interventions

Patients will be placed in an external fixator followed by open versus closed surgical stabilization of their calcaneus fracture when their soft tissue is appropriate for surgery.

External fixation
SplintingPROCEDURE

Patients will be placed in a short leg splint followed by open versus closed surgical stabilization of their calcaneus fracture when their soft tissue is appropriate for surgery.

Splinting

Eligibility Criteria

Age18 Years - 69 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Voluntary consent
  • Age 18 to 69
  • Clinical and/or advanced imaging confirming an acute calcaneal fracture that has occurred within 2 days of which, eventually definitive surgery is recommended/accepted.
  • Unable to consent

You may not qualify if:

  • Age \<18
  • Prior surgery of the affected extremity
  • Prisoners
  • Pregnant women
  • Inflammatory arthritis
  • Non-English-speaking patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of California, Davis Medical Center

Sacramento, California, 95817, United States

Location

MeSH Terms

Interventions

External FixatorsSplints

Intervention Hierarchy (Ancestors)

Orthopedic Fixation DevicesOrthopedic EquipmentSurgical EquipmentEquipment and SuppliesSurgical Fixation Devices

Limitations and Caveats

Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled.

Results Point of Contact

Title
Dr. Christopher Kreulen
Organization
University of California, Davis

Study Officials

  • Christopher D Kreulen, MD, MS

    Foot and Ankle Surgery Department of Orthopaedic Surgery University of California, Davis Medical Center

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 7, 2019

First Posted

August 21, 2019

Study Start

June 14, 2019

Primary Completion

September 3, 2019

Study Completion

September 3, 2019

Last Updated

February 9, 2022

Results First Posted

February 9, 2022

Record last verified: 2022-01

Data Sharing

IPD Sharing
Will not share

Locations