NCT04060953

Brief Summary

This study evaluates the use of a health-related quality of life report based on the SPADE cluster (sleep disturbance, pain interference with activities, anxiety, depression, and low energy/fatigue) derived from the PROMIS-29 instrument in patients with chronic low back pain. Half of the participants will receive the report, while the other half will not.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
102

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 16, 2019

Completed
Same day until next milestone

Study Start

First participant enrolled

August 16, 2019

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 19, 2019

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 14, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 14, 2020

Completed
Last Updated

February 26, 2020

Status Verified

February 1, 2020

Enrollment Period

5 months

First QC Date

August 16, 2019

Last Update Submit

February 23, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • PROMIS-29 Quality of Life Measures

    SPADE Cluster Score (acronym represents Sleep Disturbance, Pain Interference, Anxiety, Depression, and Low Energy/Fatigue subscales derived from the PROMIS-29). Each raw subscale score ranges from 4 to 20. Each subscale raw score is then converted to a population-normed "t-score," with a mean of 50 and standard deviation of 10. The SPADE Cluster Score is then computed as the mean of these five subscale t-scores. Higher t-scores on the SPADE Cluster and each of its component scales represent worse outcomes.

    3 Months Post-Randomization

Secondary Outcomes (2)

  • Low Back Pain Intensity

    3 Months Post-Randomization

  • Back-Related Disability

    3 Months Post-Randomization

Other Outcomes (1)

  • Utility of the Health-Related Quality of Life Report

    1 Month Post-Randomization

Study Arms (2)

Health-Related Quality of Life Report

EXPERIMENTAL

Participants randomized to this arm will receive the Health-Related Quality of Life Report.

Other: Health-Related Quality of Life Report

Wait List to Receive the Report

NO INTERVENTION

Participants randomized to this arm will receive the Health-Related Quality of Life Report following completion of the study.

Interventions

Subject report and interpretation guide based on SPADE cluster scores

Health-Related Quality of Life Report

Eligibility Criteria

Age21 Years - 79 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Chronic Low Back Pain based on criteria established by the NIH Task Force on Research Standards for Chronic Low Back Pain AND SPADE Cluster Score ≥ 55

You may not qualify if:

  • Absence of Chronic Low Back Pain OR SPADE Cluster Score \< 55

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of North Texas Health Science Center

Fort Worth, Texas, 76107, United States

Location

Study Officials

  • John C Licciardone, DO

    University of North Texas Health Science Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

August 16, 2019

First Posted

August 19, 2019

Study Start

August 16, 2019

Primary Completion

January 14, 2020

Study Completion

January 14, 2020

Last Updated

February 26, 2020

Record last verified: 2020-02

Data Sharing

IPD Sharing
Will not share

Locations