Value of MRI CSF Flowmetry in Assessment of Grey Zone Hydrocephalic Patients
1 other identifier
interventional
10
0 countries
N/A
Brief Summary
To evaluate accuracy of (MRI) cerebrospinal fluid flowmetry after shunt operation in patients with borderline (grey zone) hydrocephalus.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Aug 2019
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2019
CompletedFirst Submitted
Initial submission to the registry
August 13, 2019
CompletedFirst Posted
Study publicly available on registry
August 19, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2021
CompletedAugust 19, 2019
August 1, 2019
1 year
August 13, 2019
August 16, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
Decompressive changes in CT brain
CT brain showing decompression of the ventricular system in response to ventriculoperitoneal shunt
2 months
Study Arms (1)
grey zone hydrocephalic patients
OTHERMR CSF flowmetry CT brain Ventriculoperitoneal shunt
Interventions
MR flowmetry in grey zone hydro cephalic patients followed by ventriculoperitoneal shunt
Eligibility Criteria
You may qualify if:
- Patients with borderline hydrocephalus
- Clinically:suspicious and non specific symptoms as
- Headache
- Macrocranium
- Vomiting
- Gait instability
- Dementia
- Urine incontinence.
- delayed milestone.
- Radiologicaly: dilated ventricular system.
You may not qualify if:
- Documented or clinically and radiologically evident cases of hydrocephalus
- Patients known to have contraindications for MRI, e.g. an implanted magnetic device, pacemakers or claustrophobia.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (5)
Brassow F, Baumann K. Volume of brain ventricles in man determined by computer tomography. Neuroradiology. 1978;16:187-9. doi: 10.1007/BF00395246.
PMID: 310977BACKGROUNDAlgin O, Hakyemez B, Parlak M. Phase-contrast MRI and 3D-CISS versus contrast-enhanced MR cisternography on the evaluation of the aqueductal stenosis. Neuroradiology. 2010 Feb;52(2):99-108. doi: 10.1007/s00234-009-0592-x. Epub 2009 Sep 15.
PMID: 19756563BACKGROUNDVenkataramana NK. Hydrocephalus Indian scenario - A review. J Pediatr Neurosci. 2011 Oct;6(Suppl 1):S11-22. doi: 10.4103/1817-1745.85704.
PMID: 22069421BACKGROUNDBhatnagar V, George J, Mitra DK, Upadhyaya P. Complications of cerebrospinal fluid shunts. Indian J Pediatr. 1983 Mar-Apr;50(403):133-8. doi: 10.1007/BF02821431. No abstract available.
PMID: 6618572BACKGROUNDReddy GK, Bollam P, Caldito G. Long-term outcomes of ventriculoperitoneal shunt surgery in patients with hydrocephalus. World Neurosurg. 2014 Feb;81(2):404-10. doi: 10.1016/j.wneu.2013.01.096. Epub 2013 Feb 4.
PMID: 23380280BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Mohammad Taghyan
professor
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Resident at neurosurgery department
Study Record Dates
First Submitted
August 13, 2019
First Posted
August 19, 2019
Study Start
August 1, 2019
Primary Completion
August 1, 2020
Study Completion
March 1, 2021
Last Updated
August 19, 2019
Record last verified: 2019-08