Key Insights

Highlights

Success Rate

77% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

10.7%

14 terminated out of 131 trials

Success Rate

76.7%

-9.9% vs benchmark

Late-Stage Pipeline

6%

8 trials in Phase 3/4

Results Transparency

20%

9 of 46 completed with results

Key Signals

9 with results77% success14 terminated

Data Visualizations

Phase Distribution

64Total
Not Applicable (52)
P 1 (3)
P 2 (1)
P 3 (5)
P 4 (3)

Trial Status

Completed46
Unknown23
Recruiting21
Terminated14
Not Yet Recruiting12
Active Not Recruiting10

Trial Success Rate

76.7%

Benchmark: 86.6%

Based on 46 completed trials

Clinical Trials (131)

Showing 20 of 20 trials
NCT07853963Not ApplicableCompleted

Invasive Versus Non-Invasive Intracranial Pressure-Guided Management in Neurosurgical Patients

NCT06368648Recruiting

CoMind Early Feasibility Study

NCT04177914Not ApplicableActive Not RecruitingPrimary

HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants

NCT07815314Not ApplicableNot Yet RecruitingPrimary

A Prospective Study Comparing CSF Shunt Flow Between "Virtual Off" and "Flow Permissive" Shunt Valve Settings Using a Wireless, Noninvasive Shunt Flow Sensor

NCT07050628Not ApplicableRecruitingPrimary

Assessment of CSF Shunt Flow During Activities of Daily Living and Sleep With a Thermal Measurement Device

NCT07442929CompletedPrimary

Crystallization of LA and Adjuvant Mixtures in Cerebrospinal Fluid

NCT07772323Not Yet Recruiting

Bedside Cranial Ultrasound for Risk-Stratified Imaging in Pediatric Acute Brain Injury

NCT05001750Phase 1Recruiting

Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)?

NCT03327467Unknown

Expanded Access Protocol: Umbilical Cord Blood Infusions for Children With Brain Injuries

NCT04436068Not ApplicableCompletedPrimary

Hyperfine Portable MRI in Hydrocephalus and Other Conditions Prompting Outpatient Brain Imaging

NCT02230124Not ApplicableActive Not RecruitingPrimary

Magnetic Resonance Elastography in Hydrocephalus

NCT07694518Not ApplicableNot Yet RecruitingPrimary

Role of Endoscopic Third Ventriculostomy Imanagement of Hydrocephalus in Pediatric Age Group; Clinical and Surgical Outcome

NCT07679035Not ApplicableNot Yet RecruitingPrimary

Study of Shunt Flow Under Different Valve Settings Using a Wireless Sensor

NCT05068128Completed

Combined Flow and Pressure Study of Craniospinal Dynamic

NCT07630051Not ApplicableNot Yet Recruiting

Strategies for Weaning From External Ventricular Drainage

NCT06253858Not ApplicableRecruitingPrimary

Ultrasound (US) Guided External Ventricular Catheter Placement

NCT07600463Not ApplicableNot Yet RecruitingPrimary

UVC in Prevention of Surgical Wound Infection

NCT01936272Phase 3Active Not RecruitingPrimary

Randomized Controlled Trial of Shunt vs ETV/CPC for PIH in Ugandan Infants

NCT05910944Recruiting

European Study of Prodromal iNPH

NCT07547826Phase 4Not Yet RecruitingPrimary

Efficacy and Cost-Effectiveness of Topical Vancomycin Powder in Preventing Pediatric Ventriculoperitoneal Shunt Infections Across Different Etiologies

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