Effect of Protanopia on the Brightness Perception of Brake Lights

NCT04060238 | Completed

• 1 other identifier: ProLight_I
• Study Type: observational
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the offered project is to investigate the influence of protanopia (red blindness) or protanomaly (red vision weakness) on the recognizability of red brake lights with the help of a test person study. From this, estimates of the influence of protanopia or protanomaly on driving ability are to be derived. If a relevant influence can be demonstrated in the study, recommendations for action for the legislator will be made. Translated with www.DeepL.com/Translator

Conditions

Color Blindness, Red; Reaction Time

Keywords

protanopia; taillight; brake light; differential luminance sensitivity; contrast sensitivity; colour vision; colour vision defect; perimetry; semi-automated kinetic perimetry; traffic; motorist; reaction time

Outcome Measures

Primary Outcomes (1)

• Contrast sensitivity (I)

  Contrast sensitivity between taillight and brake light under two luminance conditions

  within one year

Secondary Outcomes (5)

• Reaction time

  within one year

• Contrast sensitivity (II)

  within one year

• Reaction time (II)

  within one year

• Perimetric extent of horizontal meridian

  within one year

• Loss of brightness sensation during anomaloscopic exam

  within one year

Study Arms (2)

Normal colour vision

Normal trichromopsia

Diagnostic Test: Anomaloscope (colour vision test)

Inherited red blindness

Protanopia

Diagnostic Test: Anomaloscope (colour vision test)

Interventions

Anomaloscope (colour vision test) DIAGNOSTIC_TEST

The Heidelberg Multi Colour (HMC) Anolmaloscope (Oculus Inc., Dutenhofen/FRG) is used to differentiate between normal controls (normal trichromatopsia) and test subjects with protanopia ("inherited red colour blindness")

Inherited red blindness; Normal colour vision

Eligibility Criteria

• Age: 18 Years+
• Gender Eligibility Details: male subjects only
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Ophthalmologically normal (male) subjects OR (male) subjects with (inherited) protanopia (red blindness)

You may qualify if:

• informed consent
• male
• age (greater or equal) 18 years

You may not qualify if:

• binocular (high contrast) distant visual acuity worse than 0.8 (16/20)
• spherical ametropia exceeding 8 dpt
• cylindrical ametropia exceeding 2.5 dpt
• manifest strabismus (squint) with diplopia
• relative afferent pupillary defect exceeding 0.3 log units
• anamnestic (patient history) OR morphological (slit lamp --\> anterior segment, ophthalmoscope --\> retina) clue/indicator for a ophthalmologically relevant affection of the eye OR the visual pathway
• S.p. severe ocular trauma
• Current OR s.p. severe intraocular inflammation
• S.p. intraocular surgery within the past three months

Sponsors & Collaborators

• Aalen University: lead
• Karlsruhe Institute of Technology (KIT), Karlsruhe/FRG: collaborator

Study Sites (1)

Ulrich SCHIEFER

Aalen, Deutschland, 73430, Germany

Location

MeSH Terms

Conditions

Color Vision Defects

Condition Hierarchy (Ancestors)

Vision Disorders; Sensation Disorders; Neurologic Manifestations; Nervous System Diseases; Cone Dystrophy; Eye Diseases, Hereditary; Eye Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Ulrich Schiefer, MD

  Aalen University of Applied Sciences

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 13, 2019
• First Posted: August 19, 2019
• Study Start: January 7, 2020
• Primary Completion: March 15, 2020
• Study Completion: March 15, 2020
• Last Updated: March 31, 2020

Record last verified: 2019-06

Locations

DE (1)