NCT04055805

Brief Summary

Studying the current state of the clinical approaches to bone diseases in breast cancer patients treated with adjuvant and/or hormone therapy

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
700

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2018

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 26, 2018

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

March 11, 2019

Completed
5 months until next milestone

First Posted

Study publicly available on registry

August 14, 2019

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 26, 2020

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 26, 2021

Completed
Last Updated

February 17, 2020

Status Verified

February 1, 2020

Enrollment Period

2.4 years

First QC Date

March 11, 2019

Last Update Submit

February 13, 2020

Conditions

Keywords

Aromatase InhibitorsBone pathologyQoL

Outcome Measures

Primary Outcomes (1)

  • Results from some questionnaires related to patients QoL, rated from 1 to 10.

    Description of the current state of the most frequent clinical and therapeutical approaches to bone diseases in 700 breast cancer menopausal patients treated with adjuvant and/or hormonal therapy. These patients are assessed by questionnaires regarding quality of life, menopausal status and current anti resorptive treatments

    26-32 months

Study Arms (7)

Fondazione Policlinico Universitario A. Gemelli, Roma

Polo Scienze della Salute della Donna e del Bambino

Behavioral: Observational Analysis

Università degli Studi di Pavia

Behavioral: Observational Analysis

Università di Napoli "Federico II"

Behavioral: Observational Analysis

Università degli Studi di Siena

Behavioral: Observational Analysis

Azienda Ospedaliero-Universitaria Careggi Firenze

Behavioral: Observational Analysis

Fondazione Policlinico Universitario A. Gemelli Roma

U.O.C Chirurgia Senologica

Behavioral: Observational Analysis

Istituto Nazionale dei Tumori di Napoli Fondazione G.Pascale

Behavioral: Observational Analysis

Interventions

Studying the current state of the clinical approaches to bone diseases in breast cancer patients treated with adjuvant and/or hormone therapy

Azienda Ospedaliero-Universitaria Careggi FirenzeFondazione Policlinico Universitario A. Gemelli RomaFondazione Policlinico Universitario A. Gemelli, RomaIstituto Nazionale dei Tumori di Napoli Fondazione G.PascaleUniversità degli Studi di PaviaUniversità degli Studi di SienaUniversità di Napoli "Federico II"

Eligibility Criteria

Age18 Years - 75 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility DetailsWomen
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Women affected by breast cancer in menopause or with secondary amenorrhea arising from the initiation of oncologic treatments

You may qualify if:

  • Patients willing to provide the Informed consent to participate to the study
  • Women aged 18-75 years
  • Patients having breast cancer, with no phenotype restrictions
  • Patients in natural and stable menopause
  • Patients having secondary amenorrhea, that arose after the initiation of oncologic treatment, since at least 12 months or 6 months with FSH\> 40 U/I

You may not qualify if:

  • Patients with advanced cancer and/or bone metastases and/or visceral metastases
  • Patients with severe renal insufficiency and/or in dialysis and patients affected by severe endocrine disorders

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Policlinico Agostino Gemelli

Roma, RM, 00168, Italy

RECRUITING

MeSH Terms

Conditions

Osteoporosis

Condition Hierarchy (Ancestors)

Bone Diseases, MetabolicBone DiseasesMusculoskeletal DiseasesMetabolic DiseasesNutritional and Metabolic Diseases

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

March 11, 2019

First Posted

August 14, 2019

Study Start

July 26, 2018

Primary Completion

December 26, 2020

Study Completion

October 26, 2021

Last Updated

February 17, 2020

Record last verified: 2020-02

Locations