The Becoming of Children With Doose Syndrome

NCT04048213 | Unknown

• 1 other identifier: PI2018_843_0058
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Doose syndrome is a rare epileptic syndrome that can lead to learning difficulties and a poor quality of life. The goal of this study is to evaluate the evolution of epilepsy and its consequences on cognitive development and learning issues in children with Doose syndrome.

Conditions

Doose Syndrome; Epileptic Syndromes; Learning Disabilities

Keywords

doose syndrome; Epileptic Syndromes; Learning Disabilities

Outcome Measures

Primary Outcomes (1)

• disease effects on the learning ability of children with doose syndrome

  disease effects on the learning ability of children with doose syndrome base on scholar informations

  day of inclusion

Secondary Outcomes (1)

• Evolution of epilepsy in children with doose syndrome based on pathological symptoms

  day of inclusion

Interventions

questionnaire OTHER

questionnaire send to the parents

Eligibility Criteria

• Age: 1 Year - 6 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

During this study, parents of children with Doose syndrome will receive a questionnaire regarding learning disabilities, quality of life and epilepsy of their children. Children with doose syndrome diagnosed between ages 1 and 6 and with normal development until onset of seizures will be included in this study.

You may qualify if:

• children with doose syndrome diagnosed between ages 1 and 6
• normal development until onset of seizures

You may not qualify if:

• unconfirmed diagnoses
• abnormal diagnoses
• abnormal psychomotor development before onset of seizures
• cerebral MRI abnormalities
• other child epileptic syndromes

Sponsors & Collaborators

• Centre Hospitalier Universitaire, Amiens: lead
• University Hospital, Lille: collaborator
• University Hospital, Rouen: collaborator

Study Sites (1)

CHU Amiens

Amiens, 80480, France

RECRUITING

MeSH Terms

Conditions

Epilepsies, Myoclonic; Epileptic Syndromes; Learning Disabilities

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Epilepsy, Generalized; Epilepsy; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Communication Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Neurodevelopmental Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Sylvie Nguyen, Pr

  CHRU LILLE

  PRINCIPAL INVESTIGATOR

• Axel Lebas, MD

  CHU Rouen

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Patrick Berquin, Pr

CONTACT

(33)30322087670; berquin.patrick@chu-amiens.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 6, 2019
• First Posted: August 7, 2019
• Study Start: August 1, 2019
• Primary Completion: December 1, 2023
• Study Completion: December 1, 2023
• Last Updated: April 12, 2023

Record last verified: 2023-04

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)