Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery
Randomized Controlled Study of Fever Probability, Risk Factors and Preventive Use of Non-steroidal Anti-inflammatory Drugs on Fever After Removal of Drainage Tube After Lumbar Fusion
1 other identifier
interventional
183
1 country
1
Brief Summary
This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the preventive use of non-steroidal anti-inflammatory drugs could decrease the possibility of fever happening when we remove the tube.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jun 2019
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 24, 2019
CompletedFirst Submitted
Initial submission to the registry
July 13, 2019
CompletedFirst Posted
Study publicly available on registry
August 2, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 30, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2019
CompletedJune 18, 2021
June 1, 2021
5 months
July 13, 2019
June 17, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
the rate of fever after the removal of drainage tube
we test the temperature of the patient in 24h after the removal of tube, we define fever if the temperature is higher than 37.8 degree
24 hours
Secondary Outcomes (4)
the level of WBC
24 hours
the level of CRP
24 hours
the level of ESR
24 hours
the temperature
24 hours
Study Arms (2)
Experimental Group
EXPERIMENTALpreventive use non-steroidal anti-inflammatory drugs to before the removal of drainage tube
Control Group
NO INTERVENTIONwithout any intervention when remove the drainage tube
Interventions
when we decide to remove the drainage tube, we ask the patient to take a pill of tylenol, and another pill in 12h later
Eligibility Criteria
You may qualify if:
- adult patient
- diagnosis of lumbar spinal stenosis
- perform decompression and fusion surgery and lay a drainage tube
- understand the test and could sign the name
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Peking University Third Hospital
Beijing, Haidian, 110191, China
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Yun Tian, M.D
Peking University Third Hospital, Beijing, China
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Masking Details
- Randomized control parallel
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 13, 2019
First Posted
August 2, 2019
Study Start
June 24, 2019
Primary Completion
November 30, 2019
Study Completion
December 30, 2019
Last Updated
June 18, 2021
Record last verified: 2021-06