Long-term Quality of Life Among Survivors of Sepsis in China Assessed by EQ-5D

NCT04033653 | Completed DMC

• 1 other identifier: sepsis long-term outcome
• Study Type: observational
• Target: 1,368
• Locations: 1 country
• Sites: 1

Brief Summary

Sepsis is a common critical illness in Intensive Care Unit (ICU). With the continuous progress of severe medicine, the mortality rate of ICU hospitalization for sepsis has decreased, but the long-term prognosis is not satisfied. Due to the high long-term mortality, poor physical and mental health and cognitive impairment, the long-term quality of life decreases greatly, putting great burden on the family and society. Therefore, it is of great significance to understand the epidemiology and risk factors of the long-term prognosis of sepsis and find out how to improve the prognosis .

Conditions

Sepsis

Outcome Measures

Primary Outcomes (8)

• 2-year mortality

  sepsis survivors will be followed up for 2-years

  2 year

• 2-year readmission rate

  sepsis survivors will be followed up for 2-years

  2 year

• mobility of sepsis survivors

  one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors. They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.

  2 year

• self-care of sepsis survivors

  one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors. They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.

  2 year

• usual activities of sepsis survivors

  one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors. They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.

  2 year

• discomfort or pain of sepsis survivors

  one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors. They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.

  2 year

• depression or anxiety of sepsis survivors

  one dimension of EQ-5D, which includes five dimensions and is used to evaluate the quaity of life of sepsis survivors. They are mobility， self-care，usual activities，discomfort or pain and depression or anxiety.

  2 year

• the ability to judge and memory of sepsis survivors

  It is scored by family or by yourself during telephone follow-up and is used to evaluate the quaity of life of sepsis survivors.

  2 year

Secondary Outcomes (1)

• influencing factors

  2 year

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

sepsis patients survived 90 days of oneset

You may qualify if:

• survivors in the prior study (epidemiology survey of Chinese sepsis patients)

You may not qualify if:

• : patients who are unwilling to answer or lose their interviews

Sponsors & Collaborators

• Jianfeng Xie: lead

Study Sites (1)

Zhongda hospital, Southeast University

Nanjing, Jiangsu, 210009, China

Location

MeSH Terms

Conditions

Sepsis

Condition Hierarchy (Ancestors)

Infections; Systemic Inflammatory Response Syndrome; Inflammation; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Yang Yi, Ph.D.

  Zhongda Hospital

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Attending

Study Record Dates

• First Submitted: July 7, 2019
• First Posted: July 26, 2019
• Study Start: November 1, 2015
• Primary Completion: August 1, 2018
• Study Completion: August 1, 2018
• Last Updated: July 26, 2019

Record last verified: 2019-07

Locations

CN (1)