NCT04026646

Brief Summary

In this randomized trial, the aim of study is compare acute and chronic effect of Proprioceptive Neuromuscular Facilitation stretching and static stretching in individuals with shortness hamstring in proprioception and performance. The primary outcome measurement is proprioception (position sense and motion sense), the secondary outcome measurements are physical performance evaluations. All exercises will be performed by the same physiotherapist in 8 weeks and 3 times a week. Exercises will be performed bilaterally and data from the dominant lower extremity will be used in the analysis. Exercises and assessments to reduce the effects of circadian variation will be performed at the same times during the research.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2019

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 3, 2019

Completed
16 days until next milestone

First Posted

Study publicly available on registry

July 19, 2019

Completed
3 days until next milestone

Study Start

First participant enrolled

July 22, 2019

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 10, 2022

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 8, 2022

Completed
Last Updated

January 11, 2022

Status Verified

January 1, 2022

Enrollment Period

2.5 years

First QC Date

July 3, 2019

Last Update Submit

January 10, 2022

Conditions

Flexibility

Keywords

FlexibilityProprioceptionPhysical Performance

Outcome Measures

Primary Outcomes (3)

  • Change between baseline of Knee Extension test and after 8th week

    The knee extension test will be evaluated with goniometer.

    The test will be performed 2 times. Assessment will be performed baseline and after 8th weeks. Measurement takes about 5 minutes.

  • Change between baseline of Position Sense test and after 8th week

    The position sense will be evaluated with isokinetic dynamometer.

    The test will be performed 2 times. Assessment will be performed baseline and after 8th weeks. Measurement takes about 5 minutes.

  • Change between baseline of Motion Sense and after 8th week

    The motion sense will be evaluated with isokinetic dynamometer.

    The test will be performed 2 times. Assessment will be performed baseline and after 8th weeks. Measurement takes about 5 minutes.

Secondary Outcomes (24)

  • Change between baseline of Knee Extension Test and after first stretching exercise

    Assessment will be performed baseline and after first stretching. Measurement takes about 5 minutes.

  • Change on Knee Extension Test after 6 week follow up period

    The test will be performed after 6 weeks follow up period. It takes about 5 minutes.

  • Change between baseline of Position Sense test and after first stretching exercise

    Assessment will be performed baseline and after first stretching. Measurement takes about 5 minutes.

  • Change on Position Sense test after 6 week follow up period

    The test will be performed after 6 weeks follow up period. It takes about 5 minutes.

  • Change between baseline of Motion Sense test and after first stretching exercise

    Assessment will be performed baseline and after first stretching. Measurement takes about 5 minutes.

  • +19 more secondary outcomes

Study Arms (2)

Proprioceptive Neuromuscular Facilitation stretching exercises

EXPERIMENTAL

Proprioceptive Neuromuscular Facilitation stretching exercises (contract-relax-antagonist-contract method) will be performed 6 repetition and totally 30 seconds stretching for hamstring muscle group will be performed.

Procedure: Proprioceptive Neuromuscular Facilitation stretching exercise

Static stretching exercises

EXPERIMENTAL

Passive Static Stretching exercises will be performed 2 repetition and totally 30 seconds stretching for hamstring muscle group will be performed.

Procedure: Static stretching exercise

Interventions

Proprioceptive Neuromuscular Facilitation stretching exercisePROCEDURE

Proprioceptive Neuromuscular Facilitation stretching exercises (contract-relax-antagonist-contract method) will be performed 6 repetition and totally 30 seconds stretching for hamstring muscle group will be performed.It will be applied 3 days in a week for 8 week.

Proprioceptive Neuromuscular Facilitation stretching exercises
Static stretching exercisePROCEDURE

Static stretching exercises will be applied 2 repetition. Totally 30 seconds stretching for hamstring muscle group will be performed. It will be applied 3 days in a week for 8 week.

Static stretching exercises

Eligibility Criteria

Age20 Years - 29 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Being between 20-29 years of age,
  • Male individuals,
  • Individuals who have not participated in physical activity for the last 6 months,
  • Who have the knee extension angle more than 20⁰,
  • Who accept the conditions of the study and sign the written informed consent form.

You may not qualify if:

  • Patients who have lower extremity injuries in the last 6 months,
  • Who have visual or vestibular impairments except of refractive problems,
  • Who have traumatic problems, who have rheumatologic, orthopedic or neuromuscular disease, Black people (due to muscle structure).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Eastern Mediterranean University

Mersin, 33010, Turkey (Türkiye)

RECRUITING

Related Publications (9)

  • Bouet V, Gahery Y. Muscular exercise improves knee position sense in humans. Neurosci Lett. 2000 Aug 4;289(2):143-6. doi: 10.1016/s0304-3940(00)01297-0.

    PMID: 10904140BACKGROUND

  • Hassan BS, Mockett S, Doherty M. Static postural sway, proprioception, and maximal voluntary quadriceps contraction in patients with knee osteoarthritis and normal control subjects. Ann Rheum Dis. 2001 Jun;60(6):612-8. doi: 10.1136/ard.60.6.612.

    PMID: 11350851BACKGROUND

  • Roijezon U, Clark NC, Treleaven J. Proprioception in musculoskeletal rehabilitation. Part 1: Basic science and principles of assessment and clinical interventions. Man Ther. 2015 Jun;20(3):368-77. doi: 10.1016/j.math.2015.01.008. Epub 2015 Jan 29.

    PMID: 25703454BACKGROUND

  • Ghaffarinejad F, Taghizadeh S, Mohammadi F. Effect of static stretching of muscles surrounding the knee on knee joint position sense. Br J Sports Med. 2007 Oct;41(10):684-7. doi: 10.1136/bjsm.2006.032425. Epub 2007 May 17.

    PMID: 17510229BACKGROUND

  • Bjorklund M, Hamberg J, Crenshaw AG. Sensory adaptation after a 2-week stretching regimen of the rectus femoris muscle. Arch Phys Med Rehabil. 2001 Sep;82(9):1245-50. doi: 10.1053/apmr.2001.24224.

    PMID: 11552198BACKGROUND

  • Larsen R, Lund H, Christensen R, Rogind H, Danneskiold-Samsoe B, Bliddal H. Effect of static stretching of quadriceps and hamstring muscles on knee joint position sense. Br J Sports Med. 2005 Jan;39(1):43-6. doi: 10.1136/bjsm.2003.011056.

    PMID: 15618341BACKGROUND

  • Streepey JW, Mock MJ, Riskowski JL, Vanwye WR, Vitvitskiy BM, Mikesky AE. Effects of quadriceps and hamstrings proprioceptive neuromuscular facilitation stretching on knee movement sensation. J Strength Cond Res. 2010 Apr;24(4):1037-42. doi: 10.1519/JSC.0b013e3181d09e87.

    PMID: 20300021BACKGROUND

  • Pincivero DM, Bachmeier B, Coelho AJ. The effects of joint angle and reliability on knee proprioception. Med Sci Sports Exerc. 2001 Oct;33(10):1708-12. doi: 10.1097/00005768-200110000-00015.

    PMID: 11581556BACKGROUND

  • Mani E, Kirmizigil B, Tuzun EH. Effects of two different stretching techniques on proprioception and hamstring flexibility: a pilot study. J Comp Eff Res. 2021 Sep;10(13):987-999. doi: 10.2217/cer-2021-0040. Epub 2021 Jul 7.

    PMID: 34231374DERIVED

MeSH Terms

Interventions

Muscle Stretching Exercises

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Ece Mani, MPT

    Eastern Mediterranean University

    PRINCIPAL INVESTIGATOR

  • Berkiye Kırmızıgil, DPT

    Eastern Mediterranean University

    STUDY DIRECTOR

  • Emine H Tüzün, DPT

    Eastern Mediterranean University

    STUDY DIRECTOR

Central Study Contacts

Ece Mani, MPT

CONTACT

+905488219691ece.mani13@gmail.com

Berkiye Kırmızıgil, DPT

CONTACT

+905428669679berkiye.kirmizigil@emu.edu.tr

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 3, 2019

First Posted

July 19, 2019

Study Start

July 22, 2019

Primary Completion

January 10, 2022

Study Completion

March 8, 2022

Last Updated

January 11, 2022

Record last verified: 2022-01

Locations

TU(1)