NCT04019756

Brief Summary

Identify by culture the urinary microbiota of patients with bladder cancer (at the time of diagnosis) and controls.Identify by metagenomics the urinary microbiota of patients with bladder cancer (at the time of diagnosis) and controls.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Sep 2019

Typical duration for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 9, 2019

Completed
6 days until next milestone

First Posted

Study publicly available on registry

July 15, 2019

Completed
2 months until next milestone

Study Start

First participant enrolled

September 1, 2019

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 30, 2020

Completed
1.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2021

Completed
Last Updated

July 15, 2019

Status Verified

July 1, 2019

Enrollment Period

7 months

First QC Date

July 9, 2019

Last Update Submit

July 12, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Matrix Assisted Laser Desorption Ionisation - Time of Flight

    A matrix and a sample are deposited on a target. Pulsed laser shots desorb the matrix which then ionizes the sample by charge transfer. By potential differences applied to lenses, the ionized molecules are accelerated and then transferred to the TOF analyzer. This analyzer will allow the separation of the ionized molecules which will depend on their mass-to-charge ratio.

    1 day

Study Arms (1)

Patients with cancer

50 patients ultimately diagnosed with bladder cancer and 50 control patients (diagnosis of cancer reversed at cystoscopy or cystoscopy for another cause)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Any present patient meeting the inclusion criteria of the study will be offered to participate in the study. For this purpose during the hospitalization or consultation of the patient, the investigator or his collaborator.

You may qualify if:

  • Person receiving a cystoscopy in the context of a suspicion of bladder cancer
  • Person and / or legal guardian for minors who have been informed about the study and have not expressed opposition to participate in the study.
  • Affiliated person or beneficiary of a social security scheme.

You may not qualify if:

  • Vulnerable person: pregnant, parturient or nursing woman,
  • person under guardianship or curatorship, or deprived of liberty by a judicial or administrative decision.
  • Person treated with antibiotics

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Central Study Contacts

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
OTHER
Target Duration
6 Months
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 9, 2019

First Posted

July 15, 2019

Study Start

September 1, 2019

Primary Completion

March 30, 2020

Study Completion

September 30, 2021

Last Updated

July 15, 2019

Record last verified: 2019-07