NCT04017234

Brief Summary

In Taiwan, the increasing prevalence of myopia shows a decline with age. Myopia has become a serious ocular problem in children because high myopia may lead to retinal damage, cataract and glaucoma. A prevention of myopia progression (PMP) will be developed and examined. This promotion program includes strategies such as a frequency following response, eye exercise, and transcutaneous electrical nerve stimulation on the prevention of myopia progression. Eye exercise defined as a computerized image led motion. The study aims to examine the effect of the implementation on the PMP.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
27

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2019

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 10, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 12, 2019

Completed
2 months until next milestone

Study Start

First participant enrolled

September 10, 2019

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 30, 2020

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 30, 2020

Completed
Last Updated

May 13, 2020

Status Verified

May 1, 2020

Enrollment Period

9 months

First QC Date

July 10, 2019

Last Update Submit

May 11, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • eyeball structure

    eyeball diopter detection

    one month detection after intervention

Secondary Outcomes (1)

  • vision check

    one month detection after intervention

Study Arms (2)

PMP group

EXPERIMENTAL

children received health education for eye and the intervention(which included frequency following response, eye exercise, and transcutaneous electrical nerve stimulation) a 30 minute three times per week for four weeks.

Other: frequency following response, eye exercise, and transcutaneous

control group

NO INTERVENTION

children just received health education for eye

Interventions

frequency following response, eye exercise, and TENS for 3 times per week during 4 weeks

PMP group

Eligibility Criteria

Age6 Years - 13 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • myopia is defined as the equivalent spherical surface degree of any one is less than or equal to -0.50D
  • do not use cyclogel or atropine
  • At least the eye ointment is deactivated for at least seven days
  • no plastic tablets are currently used
  • at least the plastic tablets are not allowed to be retired for more than seven days

You may not qualify if:

  • Children with current traumatic and unrecoverable other eye disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chen Pin elementary school

Taichung, 406, Taiwan

RECRUITING

MeSH Terms

Conditions

Myopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Study Officials

  • Yu-Kuei Teng

    China Medical University, Taiwan

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 10, 2019

First Posted

July 12, 2019

Study Start

September 10, 2019

Primary Completion

May 30, 2020

Study Completion

August 30, 2020

Last Updated

May 13, 2020

Record last verified: 2020-05

Locations