NCT04016818

Brief Summary

This is a research study of a novel, "breast-dedicated" positron emission tomography (PET) camera with 1 millimeter spatial resolution. The main goal of the study is for the personnel to understand practical and logistical issues with using the camera in the clinic

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at P25-P50 for early_phase_1 breast-cancer

Timeline
18mo left

Started Jun 2026

Shorter than P25 for early_phase_1 breast-cancer

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 2, 2019

Completed
10 days until next milestone

First Posted

Study publicly available on registry

July 12, 2019

Completed
6.9 years until next milestone

Study Start

First participant enrolled

June 1, 2026

Expected
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2027

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2027

Last Updated

February 10, 2026

Status Verified

February 1, 2026

Enrollment Period

1.5 years

First QC Date

July 2, 2019

Last Update Submit

February 7, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Image quality with the breast-dedicated PET camera

    Feasibility of the pilot breast-dedicated PET camera will be assessed on the basis of whether acceptable images are obtained. Images will be assessed and graded as 1 of 3 quality ratings: excellent, good, and poor. The outcome will be reported as the number of images that are excellent, good, and poor, a number without dispersion.

    1 day

Study Arms (1)

18-F FDG Study using Breast-Dedicated PET Camera

EXPERIMENTAL

Breast-Dedicated PET Camera will be used with standard PET 18-F FDG tracer dose

Drug: 18F-FDGDevice: Breast-dedicated PET camera

Interventions

Participant will be injected IV (intravenously) with 10 ± 2 mCi of 18F-FDG.

Also known as: 18F-fluorodeoxiglucose, 18F-FDG radiotracer
18-F FDG Study using Breast-Dedicated PET Camera

Breast-dedicated PET camera designed by Stanford satellite radiochemistry facility

18-F FDG Study using Breast-Dedicated PET Camera

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Biopsy-confirmed breast cancer measuring ≥ 5 mm on mammogram or ultrasound.
  • Prior diagnostic imaging test(s) with another modality such as MRI, CT, or x-ray mammography (or other applicable imaging modalities) within 60 days prior to the study date.
  • Documented written informed consent document.

You may not qualify if:

  • \. Additional condition, or extenuating circumstance that, in the opinion of the investigator, may interfere with study compliance.
  • Known allergies to FDG
  • Pregnant or nursing.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stanford University

Stanford, California, 94304, United States

Location

MeSH Terms

Conditions

Breast Neoplasms

Interventions

Fluorodeoxyglucose F18

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

DeoxyglucoseDeoxy SugarsCarbohydrates

Study Officials

  • Wendy B DeMartini

    Stanford University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
early phase 1
Allocation
NA
Masking
NONE
Purpose
DEVICE FEASIBILITY
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 2, 2019

First Posted

July 12, 2019

Study Start (Estimated)

June 1, 2026

Primary Completion (Estimated)

December 1, 2027

Study Completion (Estimated)

December 1, 2027

Last Updated

February 10, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Locations