Pleth Variability Index in Modified Prone Position or Knee-chest Position (Concord Position)

NCT04002193 | Completed

• 1 other identifier: HePark
• Study Type: observational
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

To investigate whether PVI predicts the fluid responsiveness in modified prone position undergoing posterior approach cervical operation. Furthermore, modified prone position could influence on dynamic variables including stroke volume variation(SVV), pulse pressure variation(PPV) and PVI.

Conditions

Fluid Responsiveness; Modified Prone Position

Keywords

Pleth variability index

Outcome Measures

Primary Outcomes (1)

• To assess influence of the position change on PVI and other variables(PPV, SVV)

  When position change from supine to modified prone position, to assess the change of PVI and other variables. The correlation of PVI and cardiac output during this change.

  1.supine position : 5 minute after anesthesia induction with arterial-line insertion 2. 5 min after crystalloid 4 ml/kg loading / 3. modified prone position (baseline)

Secondary Outcomes (1)

• To measure dynamic variables (pulse pressure variation, stroke volume variation and pleth variability index) in modified prone position

  1. Supine position : 5 minute after anesthesia induction with arterial-line insertion 2. 5 minute after a position change to prone 3. before and after fluid loading

Interventions

volume expansion OTHER

To assess fluid responsiveness

Also known as: If stroke volume of FloTrac® decrease 15 % of baseline, crystalloid loading of 4ml/kg will start.

Eligibility Criteria

• Age: 19 Years - 79 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients received cervical operation at modified prone position (concord position)

You may qualify if:

• American Society of Anaesthesiologists'(ASA) physical status 1-3
• patients who received cervical operation in modified prone position or knee-chest position

You may not qualify if:

• Valvular heart disease
• Congestive heart failure, reduced left ventricular function ( Ejection fraction \< 40%)
• Moderate grade of pulmonary disease
• Arrhythmia (atrial fibrillation, atrial flutter.. etc.)
• body mass index \> 30 or \< 15 kg/m2

Sponsors & Collaborators

• Asan Medical Center: lead

Study Sites (1)

Asan Medical Center

Seoul, Songpa-gu, South Korea

Location

MeSH Terms

Interventions

BaseLine dental cement

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical instructor of Anesthesiology and Pain department

Study Record Dates

• First Submitted: May 24, 2019
• First Posted: June 28, 2019
• Study Start: December 6, 2019
• Primary Completion: October 26, 2020
• Study Completion: October 31, 2020
• Last Updated: March 24, 2022

Record last verified: 2022-03

Locations

KR (1)