Self-estimates and Objective Blood Alcohol Concentration in Emergency Department

NCT03998397 | Completed

• 1 other identifier: PI2018_843_0009
• Study Type: interventional
• Target: 34
• Locations: 1 country
• Sites: 1

Brief Summary

Many patients presenting in Emergency Department (ED) present alcohol acute intoxication. Some previous studies in general population found that young people under- or over-estimated of blood alcohol concentration (BAC). The hypothesis of the study is that self-estimation of BAC by the patient is under-estimated. Moreover, comparing self-estimation of BAC and objective measure of BAC, which is routinely performed in ED, could increase in patients the awareness of the disorders, increase motivation to change of the patient, and increase the rates of seeking-treatment six months after the first evaluation, in particular in patients with alcohol use disorders. To the investigators knowledge, there is no study investigating self-estimation, compared to objective measurement of blood alcohol concentration in patients with alcohol intoxication presenting to an Emergency Department (ED). The study will assess blood alcohol concentration and self-estimates of BAC, using the Subjective Effects of Alcohol Scale for Measuring Subjective Response to Alcohol in 100 patients with or without alcohol use disorders according to DSM-5 classification (using MINI scale and Alcohol Use Disorders Identification Test (AUDIT)

Conditions

Alcohol Use Disorder; Blood Alcohol Content

Keywords

blood alcohol concentration; Emergency Department; Alcohol use disorders

Outcome Measures

Primary Outcomes (1)

• Mean change between real blood alcohol concentration and self-estimated blood alcohol concentration

  Comparison of real blood alcohol concentration and self-estimated blood alcohol concentration

  Day =0 (day of patient inclusion)

Secondary Outcomes (4)

• Mean change between real blood alcohol concentration and self-estimated blood alcohol concentration in patient with alcohol use disorders

  Day =0 (day of patient inclusion)

• Mean change between real blood alcohol concentration and self-estimated blood alcohol concentration in patient without alcohol use disorders

  Day =0 (day of patient inclusion)

• Measure motivation to change during the first interview at the Emergency Department

  Day =0 (day of patient inclusion)

• Measure motivation to change six months following the first interview at the Emergency Department

  six months following the first interview at the Emergency Department

Study Arms (2)

patients with alcohol use disorders

EXPERIMENTAL

Biological: blood alcohol concentration withdrawal

patients without alcohol use disorders

EXPERIMENTAL

Biological: blood alcohol concentration withdrawal

Interventions

blood alcohol concentration withdrawal BIOLOGICAL

The blood alcohol concentration is systematically performed in all intoxicated patients admitted in Emergency Department

patients with alcohol use disorders; patients without alcohol use disorders

Eligibility Criteria

• Age: 15 Years - 64 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Patients admitted in Emergency Department while intoxicated will be included in the study, including patients with or without alcohol use disorders according to DSM-5 classification.
• aged 15-64 years old
• patients who will be orally informed and receive a written summary
• blood alcohol concentration of 60mg/dl or higher
• Patients not opposed to participating in the study, who have received an oral and written information

You may not qualify if:

• Drug intoxication (cannabis, opiates, amphetamines, cocaine), psychotropic medication intoxication (benzodiazepines, antipsychotics), primary neurologic conditions, mental retardation, dementia, amnestic disorders, mental disorders due to a general, medical condition and substance-induced psychotic disorders.

Sponsors & Collaborators

• Centre Hospitalier Universitaire, Amiens: lead

Study Sites (1)

CHU Amiens

Amiens, 80480, France

Location

Related Publications (1)

• DOI:10.1016/j.euroneuro.2020.09.032 November 2020European Neuropsychopharmacology 40(4):S20 P.029 Self-estimation of blood alcohol concentration in patients admitted for acute alcohol intoxication in emergency department

  RESULT

MeSH Terms

Conditions

Alcoholism; Emergencies

Interventions

Blood Specimen Collection; Ethanol

Condition Hierarchy (Ancestors)

Alcohol-Related Disorders; Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Specimen Handling; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Punctures; Surgical Procedures, Operative; Investigative Techniques; Alcohols; Organic Chemicals

Study Officials

• Alain Dervaux, Pr

  CHU Amiens

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 21, 2019
• First Posted: June 26, 2019
• Study Start: June 18, 2019
• Primary Completion: June 18, 2020
• Study Completion: June 18, 2020
• Last Updated: November 19, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)