NCT03985839

Brief Summary

This is a prospective, multi-center, PMCF study to evaluate the safety and performance of the MICRORAPTOR REGENESORB suture anchors, MICRORAPTOR Knotless REGENESORB suture anchors, and MICRORAPTOR Knotless PEEK suture anchors implanted in 300 subjects needing reattachment of soft tissue to bone.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
299

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Aug 2019

Longer than P75 for all trials

Geographic Reach
1 country

12 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 11, 2019

Completed
3 days until next milestone

First Posted

Study publicly available on registry

June 14, 2019

Completed
2 months until next milestone

Study Start

First participant enrolled

August 1, 2019

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 8, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 8, 2024

Completed
Last Updated

March 17, 2025

Status Verified

November 1, 2023

Enrollment Period

5 years

First QC Date

June 11, 2019

Last Update Submit

March 14, 2025

Conditions

Keywords

Microraptor, suture anchor, knotless, Smith and Nephew

Outcome Measures

Primary Outcomes (1)

  • Repair failure rate

    To assess repair failure rate at 6 months

    6 months

Secondary Outcomes (8)

  • Repair failure rate

    12 months

  • ROWE shoulder score

    6 and 12 months

  • WOSI shoulder score

    6 and 12 months

  • Constant-Murley Shoulder Scale

    6 and 12 months

  • HOS-ADL Score

    6 and 12 months

  • +3 more secondary outcomes

Study Arms (3)

MICRORAPTOR™ REGENESORB™ Suture Anchor

MICRORAPTOR™ REGENESORB™ Suture Anchor

Device: MICRORAPTOR™ REGENESORB™ Suture Anchor

MICRORAPTOR™ Knotless REGENESORB™ Suture Anchor

MICRORAPTOR™ Knotless REGENESORB™ Suture Anchor

Device: MICRORAPTOR™ Knotless REGENESORB™ Suture Anchor

MICRORAPTOR™ Knotless PEEK Suture Anchor

MICRORAPTOR™ Knotless PEEK Suture Anchor

Device: MICRORAPTOR™ Knotless PEEK Suture Anchor

Interventions

Smith \& Nephew MICRORAPTOR™ REGENESORB™ Suture Anchor is a fixation device intended to provide secure attachment of soft tissue to bone.

MICRORAPTOR™ REGENESORB™ Suture Anchor

MICRORAPTOR™ Knotless REGENESORB™ Suture Anchor is fixation device, which consists of an anchor on an inserter, and a suture threader. The anchor consists of the following components: a proximal anchor body (REGENESORB™), and a non-absorbable PEEK (Polyether ether ketone) distal anchor tip.

MICRORAPTOR™ Knotless REGENESORB™ Suture Anchor

The MICRORAPTOR™ Knotless PEEK Suture Anchor is a class IIb device, which consists of an anchor on an inserter, and a suture threader. The anchor consists of the following components: a proximal anchor body (PEEK), and a non-absorbable PEEK distal anchor tip.

MICRORAPTOR™ Knotless PEEK Suture Anchor

Eligibility Criteria

Age12 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Subject requires reattachment of soft tissue to bone for the following indications: * Shoulder - Capsular stabilization for Bankart repair, Anterior shoulder instability, SLAP lesion repairs, Capsular shift or capsulolabral reconstructions, Biceps tenodesis, Rotator Cuff Repairs (knotless anchors only) * Hip - Acetabular labrum repair/reconstruction

You may qualify if:

  • Subject requires reattachment of soft tissue to bone for the following indications:
  • Shoulder - Capsular stabilization for Bankart repair, Anterior shoulder instability, SLAP lesion repairs, Capsular shift or capsulolabral reconstructions, Biceps tenodesis, Rotator Cuff Repairs (knotless anchors only)
  • Hip - Acetabular labrum repair/reconstruction
  • Subject has consented to participate in the study by signing the EC-approved informed consent form.
  • Subject is ≥18 years of age at time of surgery.
  • Willing and able to make all required study visits.
  • Able to follow instructions.

You may not qualify if:

  • Known hypersensitivity to the implant material. Where material sensitivity is suspected, appropriate tests should be made and sensitivity ruled out prior to implantation.
  • Pathological conditions of bone, such as cystic changes or severe osteopenia, which would compromise secure anchor fixation.
  • Pathological conditions in the soft tissues to be attached that would impair secure fixation by suture.
  • Comminuted bone surface, which would compromise secure anchor fixation.
  • Physical conditions which would eliminate, or tend to eliminate, adequate anchor support or retard healing.
  • The presence of infection.
  • Conditions which would limit the subject's ability or willingness to restrict activities or follow directions during the healing period.
  • Currently using tobacco products (cigarette, smokeless tobacco, ecigarettes, vaping etc.).
  • Concurrent bilateral surgery.
  • Prior MICRORAPTOR REGENESORB, MICRORAPTOR Knotless REGENESORB, or MICRORAPTOR Knotless PEEK implantation.
  • Participation in the treatment period of another clinical trial within thirty (30) days of Visit 1, or during the study.
  • Women who are pregnant or nursing.
  • History of poor compliance with medical treatment.
  • Prior ipsilateral surgeries performed on the joint space.
  • Subjects with a medical or physical condition that, in the opinion of the Investigator, would preclude safe subject participation in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (12)

University of Colorado

Aurora, Colorado, 80045, United States

Location

Colorado Springs Orthopaedic Group

Colorado Springs, Colorado, 80920, United States

Location

Holy Cross Orthopedic Institute

Oakland Park, Florida, 33334, United States

Location

Emory University - Brookhaven

Brookhaven, Georgia, 30329, United States

Location

Luminis Health Research Institute

Annapolis, Maryland, 21401, United States

Location

Ohio State University Wexner Medical Center

Columbus, Ohio, 43202, United States

Location

Oklahoma Sports and Science Orthopedics / The Physician's Group

Oklahoma City, Oklahoma, 73114, United States

Location

Palmetto/Prisma Health - University of South Carolina Orthopaedics

Columbia, South Carolina, 29203, United States

Location

Steadman Hawkins Clinic of the Carolinas

Greenville, South Carolina, 29615, United States

Location

Atlantic Orthopaedic Specialists

Virginia Beach, Virginia, 23452, United States

Location

Center for Advanced Orthopaedics / Nova Orthopedic & Spine Care

Woodbridge, Virginia, 22191, United States

Location

Memorial Medical Center

Ashland, Wisconsin, 54806, United States

Location

MeSH Terms

Conditions

Rotator Cuff InjuriesBankart Lesions

Condition Hierarchy (Ancestors)

RuptureWounds and InjuriesShoulder InjuriesTendon InjuriesShoulder FracturesFractures, Bone

Study Officials

  • Mary Ozokwere

    Smith & Nephew, Inc.

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 11, 2019

First Posted

June 14, 2019

Study Start

August 1, 2019

Primary Completion

August 8, 2024

Study Completion

August 8, 2024

Last Updated

March 17, 2025

Record last verified: 2023-11

Data Sharing

IPD Sharing
Will not share

Locations