The Effects of Whole Body Vibration in People With Chronic Stroke
1 other identifier
interventional
80
1 country
1
Brief Summary
Whole body vibration (WBV) has been found to be useful in promoting bone health and muscle performance in older adults. To date, no study has examined the effects of different WBV frequencies on the properties of the muscle-bone unit in stroke patients. The overall aim of the proposed study is to compare the efficacy of different vibration frequencies on properties of the muscle function and bone turnover among people with chronic stroke. It is hypothesized that the higher-vibration frequency protocol will lead to significantly better outcomes related to the bone turnover and muscle function.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable stroke
Started Jun 2017
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 28, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 28, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
August 28, 2018
CompletedFirst Submitted
Initial submission to the registry
June 6, 2019
CompletedFirst Posted
Study publicly available on registry
June 11, 2019
CompletedJune 11, 2019
June 1, 2019
1 year
June 6, 2019
June 9, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
bone resorption marker
Serum level of aminoterminal crosslinked telopeptide
pre-test (week 0)
bone resorption marker
Serum level of aminoterminal crosslinked telopeptide
post-test (week8)
Secondary Outcomes (6)
Six Minute Walk Test
pre-test (week 0)
Six Minute Walk Test
post-test (week8)
Gait velocity
pre-test (week 0)
Gait velocity
post-test (week8)
Spasticity
pre-test (week 0)
- +1 more secondary outcomes
Study Arms (2)
High frequency whole body vibration
EXPERIMENTALThis group will receive a single 8-minute session of WBV therapy. The frequency of the vibration signals will be set at 30Hz.
low frequency whole body vibration
ACTIVE COMPARATORThis group will receive a single 12-minute session of WBV. The frequency of the vibration signals will be set at 20 Hz.
Interventions
1 single session ( 8 minutes) of whole body vibration therapy at 30 Hz
1 single session ( 12 minutes) of whole body vibration therapy at 20 Hz
Eligibility Criteria
You may qualify if:
- a diagnosis of stroke
- stroke onset \>6 months
- \>18 years of age
- able to walk for short distance independently with or without walking aid
- able to understand simple verbal commands
You may not qualify if:
- neurological conditions other than stroke
- significant musculoskeletal conditions (e.g. amputations)
- metal implants in the lower extremity
- previous fracture of the lower extremity
- are currently taking bone resorption inhibitors or were taking the same before stroke.
- significant peripheral vascular disease
- vestibular disorders
- pregnancy
- Other serious illnesses that preclude the person from participating in the study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
The Hong Kong Polytechnic University
Hong Kong, Hong Kong
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Marco YC Pang, PhD
The Hong Kong Polytechnic University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
June 6, 2019
First Posted
June 11, 2019
Study Start
June 28, 2017
Primary Completion
June 28, 2018
Study Completion
August 28, 2018
Last Updated
June 11, 2019
Record last verified: 2019-06