Presentation of Subarachnoid Haemorrhage

NCT03980613 | Completed

• 1 other identifier: STPS 3-3013-2947/1
• Study Type: observational
• Target: 892
• Locations: 1 country
• Sites: 1

Brief Summary

It is the primary aim of this study to identify symptoms and/or specific words (trigger words) indicative of spontaneous subarachnoid haemorrhage (sSAH) during emergency telephone calls to the Emergency Medical Service Copenhagen (EMS). Further, it is the aim to determine the association between the symptoms/trigger words and sSAH, the sensitivity of the symptoms/trigger words and finally, to identify factors in the telephone visitation that may influence the level of activated prehospital response

Conditions

Subarachnoid Hemorrhage

Keywords

Emergency Medical Service; Triage; Telephone visitation

Outcome Measures

Primary Outcomes (1)

• Proportions of patients with each symptom

  The proportions of patients presenting with each identified symptom and/or trigger word described during emergency telephone calls, among patients with first-ever sSAH.

  Day 0

Secondary Outcomes (3)

• Odds ratios for having sSAH for each symptom identified under the primary outcome.

  Day 0

• Sensitivity of each symptom.

  Day 0

• Emergency telephone call predictors for dispatching ambulances with the highest priority level.

  Day 0

Study Arms (2)

Spontaneous subarachnoid haemorrhage

Patients with verified spontaneous subarachnoid haemorrhage that have called the emergency medical service Copenhagen.

Other: Triage

Controls

Patients without spontaneous subarachnoid haemorrhage that have called the emergency medical service Copenhagen.

Other: Triage

Interventions

Triage OTHER

Emergency telephone calls from cases and controls are replayed and analyzed for symptom descriptions indicating spontaneous subarachnoid haemorrhage.

Controls; Spontaneous subarachnoid haemorrhage

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

People aged 18 years or older with a Danish Central Person Register-number (CPR-number), living, working or visiting the Capital Region of Denmark between January 1, 2014 and December 31, 2018.

You may qualify if:

• Having called the emergency medical service Copenhagen between January 1, 2014 and December 31, 2018.
• Must have a Danish Central Person Register-number.
• Cases must be first-ever subarachnoid haemorrhages.
• Cases must have survived to admission.

You may not qualify if:

• Patients transferred to a to a hospital in the Capital Region of Denmark from abroad or from another Danish geopolitical region.
• Subarachnoid haemorrhages that have occurred during hospitalization are also excluded.

Sponsors & Collaborators

• Rigshospitalet, Denmark: lead
• Emergency Medical Services, Capital Region, Denmark: collaborator

Study Sites (1)

Rigshospitalet

Copenhagen, Denmark

Location

Related Publications (1)

• Sonne A, Egholm S, Elgaard L, Breindahl N, Jensen AH, Eskesen V, Lippert F, Waldorff FB, Lohse N, Rasmussen LS. Symptoms presented during emergency telephone calls for patients with spontaneous subarachnoid haemorrhage. Scand J Trauma Resusc Emerg Med. 2021 Aug 16;29(1):118. doi: 10.1186/s13049-021-00934-x.

  PMID: 34399811 DERIVED

MeSH Terms

Conditions

Subarachnoid Hemorrhage

Interventions

Triage

Condition Hierarchy (Ancestors)

Intracranial Hemorrhages; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Hemorrhage; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Emergency Medical Services; Health Services; Health Care Facilities Workforce and Services

Study Officials

• Lars S Rasmussen, Professor

  Rigshospitalet, Capital Region of Denmark

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: June 4, 2019
• First Posted: June 10, 2019
• Study Start: August 26, 2019
• Primary Completion: December 31, 2020
• Study Completion: December 31, 2020
• Last Updated: February 25, 2021

Record last verified: 2021-02

Data Sharing

• IPD Sharing: Will not share

Locations

DK (1)