NCT03976765

Brief Summary

Monocentric, prospective study to evaluate 10 liver transplanted patients

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Dec 2018

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 17, 2018

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

June 4, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 6, 2019

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 11, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 11, 2020

Completed
Last Updated

April 15, 2021

Status Verified

April 1, 2021

Enrollment Period

1.7 years

First QC Date

June 4, 2019

Last Update Submit

April 14, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Number of patients with an hospital discharge at day 7

    Day 7

Secondary Outcomes (5)

  • Number of patients readmission in the first month

    Month 1

  • Number of days of hospitalization during the first month (post-surgery and prehospitalization)

    Month 1

  • Number of death in the first month

    Month 1

  • Satisfaction of the patient in the first month

    Month 1

  • Number of surgery complications according to Dindo and Clavien classification during the first month

    Month 1

Study Arms (1)

Hospital discharge at day 7

Other: Rehabilitation program

Interventions

The patients follow different rehabilitation programs (surgery, anesthetic, post-operative). Hospital discharge is authorized only after validation of objective, clinical and para clinic criteria

Hospital discharge at day 7

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Liver transplant patients

You may qualify if:

  • Patient older than 18 years old
  • First liver transplant
  • Liver transplant alone
  • MELD (Model for End stage Liver Disease) score ≤ 15
  • CHILD-PUGH score ≤ 8 if cirrhosis
  • Body Mass Index \< 30 kg/m2
  • No history of transplant nor immunosuppression
  • Absence of ascites nor hydrothorax drain
  • Absence of treatment for diabetes
  • Absence of renal insufficiency (glomerular filtration flow \> 60 mL/min)
  • Family help at home

You may not qualify if:

  • Cold ischemia time \> 8 hours
  • Grafts from type III Maastricht
  • Super urgent liver transplantation
  • Perioperative blood transfusion \> 4 packed red blood cells and/or 3 fresh frozen plasma
  • Arterial anastomosis in splenic artery, in aorta or in coeliac artery
  • Bilio-digestive anastomosis
  • Persons deprived of liberty
  • Pregnant or breastfeeding women

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU de Rennes

Rennes, 35033, France

Location

MeSH Terms

Interventions

Rehabilitation

Intervention Hierarchy (Ancestors)

AftercareContinuity of Patient CarePatient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and Services

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 4, 2019

First Posted

June 6, 2019

Study Start

December 17, 2018

Primary Completion

August 11, 2020

Study Completion

August 11, 2020

Last Updated

April 15, 2021

Record last verified: 2021-04

Data Sharing

IPD Sharing
Will not share

Locations