NCT03976232

Brief Summary

Sleep problems in patients with CLBP are a very common complication and is the most neglected part of the management. Though previous literature suggested that sleep problems need to be managed in patients with CLBP, no physical therapy or manual therapy techniques has been checked for their efficacy to manage the same. Therefore, there is a need to check the efficacy of various physical therapy and manual therapy techniques so that sleep problems associated with CLBP can be managed effectively by physical means. The main purpose of the study is to check the efficacy of tDCS and CST to improve sleep, pain and quality of life in patients with CLBP.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2019

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 27, 2019

Completed
5 days until next milestone

Study Start

First participant enrolled

June 1, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 5, 2019

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 30, 2021

Completed
3 days until next milestone

Study Completion

Last participant's last visit for all outcomes

February 2, 2021

Completed
Last Updated

June 5, 2019

Status Verified

June 1, 2019

Enrollment Period

1.7 years

First QC Date

May 27, 2019

Last Update Submit

June 4, 2019

Conditions

Outcome Measures

Primary Outcomes (2)

  • Polysomnography

    Polysomnographic parameters will be recorded.

    changes between baseline to 2 weeks and 6 weeks

  • Pittsburgh sleep quality Index scale.

    Qualitative assessment of sleep will be recorded by this scale

    changes between baseline to 2 weeks and 6 weeks

Secondary Outcomes (2)

  • Modified Oswestry disability index

    changes between baseline to 2 weeks and 6 weeks

  • NPRS

    changes between baseline to 2 weeks and 6 weeks

Study Arms (3)

tDCS-Group

EXPERIMENTAL

Participants of this arm will receive tDCS and Conventional therapy for 2 weeks.

Device: Trans cranial Direct Current Stimulation (tDCS)

CST- Group

EXPERIMENTAL

Participants of this arm will receive CST and Conventional therapy for 2 weeks.

Other: Craniosacral therapy (CST)

combination of tDCS and CST

ACTIVE COMPARATOR

Participants of this arm will receive CST+ tDCS and Conventional therapy for 2 weeks.

Other: tDCS+ CST

Interventions

Active tDCS will be applied for 20 minutes with 2 mA intensity. Anode will be placed at left dorsolateral prefrontal cortex and cathode will be placed at the right cerebellar cortex.

tDCS-Group

Craniosacral therapy will be given to all the participants which includes release of all major diaphragm, frontal lift, parietal lift, occipital lift, CV4 and dural tube rocking.

CST- Group

This group will receive tDCS along with CST

combination of tDCS and CST

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • People with chronic low back pain (more than 3 months)
  • Both males and females.
  • years
  • Able to follow verbal commands.

You may not qualify if:

  • Diagnosed with primary sleep disorders
  • Pregnancy
  • Taking any medication for a psychological disorder
  • Acute or subacute LBP
  • Diagnosed with any other systemic disorder.
  • Spinal tumour.
  • Radicular pain and nerve root compression.
  • Severe spinal stenosis, spondylolisthesis, fibromyalgia.
  • Unstable angina and other cardiovascular disorders.
  • Malignancy.
  • History of other systemic and inflammatory disease.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Parasomnias

Condition Hierarchy (Ancestors)

Sleep Wake DisordersNervous System DiseasesMental Disorders

Central Study Contacts

Subhasish Chatterjee, MPT

CONTACT

Vandana Esht, Ph.D

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
SEQUENTIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Subhasish Chatterjee

Study Record Dates

First Submitted

May 27, 2019

First Posted

June 5, 2019

Study Start

June 1, 2019

Primary Completion

January 30, 2021

Study Completion

February 2, 2021

Last Updated

June 5, 2019

Record last verified: 2019-06

Data Sharing

IPD Sharing
Will not share