NCT03970863

Brief Summary

To evaluate the cancer control for prostate cancer patients treated with focal therapy.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Aug 2020

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 27, 2019

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 3, 2019

Completed
1.2 years until next milestone

Study Start

First participant enrolled

August 1, 2020

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 10, 2020

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

November 10, 2021

Completed
Last Updated

February 9, 2024

Status Verified

February 1, 2024

Enrollment Period

3 months

First QC Date

May 27, 2019

Last Update Submit

February 7, 2024

Conditions

Outcome Measures

Primary Outcomes (2)

  • oncological outcome

    MR/US fusion prostate biopsy to see if there is recurrent cancer

    6 months

  • biochemical outcome

    change of Prostate Health Index (PSA, free PSA, and p2PSA will be combined to report PHI)

    1 month, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months, 24 months

Secondary Outcomes (5)

  • Functional outcome

    1 month, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months, 24 months

  • Functional outcome

    1 month, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months, 24 months

  • Functional outcome

    1 month, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months, 24 months

  • Functional outcome

    1 month, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months, 24 months

  • Functional outcome

    1 month, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months, 24 months

Interventions

Prostate Health IndexDIAGNOSTIC_TEST

Use Prostate Health Index for the follow-up after focal therapy.

Eligibility Criteria

Age40 Years - 90 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

prostate cancer patients in a tertiary referral center in Taiwan

You may qualify if:

  • biopsy-proven unilateral prostate cancer, the other side insignificant cancer (Gleason 6 or less and maximal cancer core length 4mm or less) is allowed
  • clinical T2a or less
  • Gleason 4+3 or less
  • serum PSA less than 20 ng/mL

You may not qualify if:

  • T2b or higher
  • Gleason 4+4 or higher
  • serum PSA 20 or higher
  • lymph node or distant metastasis
  • previous treatment with prostatectomy, radiotherapy, androgen deprivation therapy, HIFU, or cryoablation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

China Medical University Hospital

Taichung, 404, Taiwan

Location

MeSH Terms

Conditions

Prostatic Neoplasms

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital Diseases

Study Officials

  • Po-Fan Hsieh

    China Medical University Hospital

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Attending Urologist, Department of Urology, China Medical University Hospital

Study Record Dates

First Submitted

May 27, 2019

First Posted

June 3, 2019

Study Start

August 1, 2020

Primary Completion

November 10, 2020

Study Completion

November 10, 2021

Last Updated

February 9, 2024

Record last verified: 2024-02

Locations