Longstanding Eating Disorders and Personality Disorders

NCT03968705 | Active Not Recruiting

• 1 other identifier: ModumBad
• Study Type: observational
• Target: 86
• Locations: 0 countries
• Sites: N/A

Brief Summary

Background Eating disorders rank among the ten leading causes of disability among young women, and anorexia nervosa has the highest mortality rate of all mental disorders. Follow-up studies have shown that 20-30 % of patients with eating disorders develop longstanding symptoms, seriously impairing their daily and represents a public health concern. There are very few studies on the course of these patients. Several studies have demonstrated comorbidity between eating disorders and personality disorders. Among patients with eating disorders, the reported frequencies of personality disorders vary from 27% to 77%. Most of the studies are cross-sectional designs, thus unable to catch trends or changes over time. There is a need for prospective longitudinal studies of adult patients using structured diagnostic interviews both for eating disorders and personality disorders. At Modum Bad, a Norwegian psychiatric hospital, the investigators have conducted a follow-up study of patients with longstanding eating disorder 1-, 2- and 5-years after treatment. The aim of the present project is to follow-up the patients additional 17-years after treatment. Objective Investigate the 17-years course and outcome of adult patients with severe and longstanding eating disorders with regard to eating disorder-related symptoms, general symptoms and personality disorders in addition to examining whether personality disorders and sexual abuse in childhood can predict the course and outcome. Method Examining patients 17-years after treatment with standardized interviews and questionnaires.

Conditions

Feeding and Eating Disorders

Outcome Measures

Primary Outcomes (1)

• Change in number of patients no longer fulfilling criteria for an eating disorder diagnosis

  Frequency of patients no longer fulfilling criteria for an eating disorder diagnosis based on structured interviews

  Admission, after 6-months of treatment, 1-year after treatment, 2-year after treatment, 5-year after treatment and 17-year after treatment

Secondary Outcomes (2)

• Frequencies of bingeing and compensating behaviour

  Admission, after 6-months of treatment, 1-year after treatment, 2-year after treatment, 5-year after treatment and 17-year after treatment

• Number of patients in recovery status based on BMI, Eating Disorder Examination global score and Frequencies of bingeing and compensating behaviour

  Admission, after 6-months of treatment, 1-year after treatment, 2-year after treatment, 5-year after treatment and 17-year after treatment

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients with longstanding eating disorder

You may qualify if:

• Symptoms of anorexia nervosa, bulimia nervosa, and eating disorder not otherwise specified that impaired daily functioning
• Inadequate responses to previous treatment
• Age above 18

You may not qualify if:

• Serious medical complication
• Body mass index (BMI) below 14

Sponsors & Collaborators

• Modum Bad: lead
• The Norwegian Women´s Public Health Association: collaborator

Related Publications (1)

• Eielsen HP, Vrabel K, Hoffart A, Ro O, Rosenvinge JH. Reciprocal relationships between personality disorders and eating disorders in a prospective 17-year follow-up study. Int J Eat Disord. 2022 Dec;55(12):1753-1764. doi: 10.1002/eat.23823. Epub 2022 Oct 10.

  PMID: 36214278 DERIVED

MeSH Terms

Conditions

Feeding and Eating Disorders

Condition Hierarchy (Ancestors)

Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Mental Disorders

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 30, 2019
• First Posted: May 30, 2019
• Study Start: January 1, 1998
• Primary Completion: March 31, 2021
• Study Completion: December 30, 2025
• Last Updated: May 8, 2025

Record last verified: 2025-05